Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883811 | 0.89 | ALAD (0.35) | LDHARXRARXRBRXRGKDM4E | |
| SCHEMBL28800023 | 0.71 | LDHA (0.44) | LDHAHDAC6GLO1RBP4TTR | |
| SCHEMBL6502438 | 0.63 | CRHBP (0.48) | LDHAHDAC6AR | |
| SCHEMBL26373459 | 0.63 | KIF11 (0.46) | LDHAHDAC6KDM4EALDH1A1GAA | |
| SCHEMBL28678059 | 0.63 | KIF11 (0.46) | LDHAHDAC6GLO1RXRARXRB | |
| SCHEMBL31369064 | 0.61 | ACMSD (0.59) | LDHAHDAC6RXRARXRBRXRG | |
| SCHEMBL3582859 | 0.61 | ACMSD (0.59) | LDHAHDAC6RXRARXRBRXRG | |
| SCHEMBL28566197 | 0.61 | KIF11 (0.50) | LDHAHDAC6RXRARXRBRXRG | |
| SCHEMBL7624 | 0.61 | LDHA (1.00) | LDHAHDAC6GLO1RXRARXRB | |
| SCHEMBL27702500 | 0.60 | RXRA (0.49) | LDHAHDAC6RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | claimed |
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |