Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883809 | 0.89 | ALK (0.36) | LDHATTRFFAR2NOTUMRXRA | |
| SCHEMBL27883829 | 0.80 | NOTUM (0.47) | TTRNOTUMAGTR2RBP4GAA | |
| SCHEMBL27867409 | 0.74 | AGTR2 (0.52) | AGTR2 | |
| SCHEMBL27867449 | 0.71 | MMP8 (0.43) | GLO1NOTUMS1PR5AGTR2 | |
| SCHEMBL27867446 | 0.71 | LDHA (0.43) | LDHATTRHDAC6GLO1RXRA | |
| SCHEMBL27867427 | 0.70 | UCHL1 (0.41) | AGTR2 | |
| SCHEMBL27867498 | 0.70 | AGTR2 (0.51) | AGTR2 | |
| SCHEMBL27883831 | 0.69 | XIAP (0.42) | AGTR2 | |
| SCHEMBL27883834 | 0.69 | AADAT (0.51) | NOTUMAGTR2GAA | |
| SCHEMBL27883822 | 0.69 | OPRD1 (0.43) | FFAR2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | claimed |
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |