Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 2/20 | 0.41 |
| ▸ | TUBB known ✓ | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B known ✓ | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A known ✓ | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B known ✓ | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 known ✓ | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A known ✓ | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A known ✓ | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144513 | 0.88 | GPR84 (0.46) | F7F3GPR84NR4A2PYGL | |
| SCHEMBL27960056 | 0.84 | F7 (0.51) | F7F3GPR84NR4A2PYGL | |
| SCHEMBL28034475 | 0.83 | F7 (0.50) | F7F3GPR84NR4A2PYGL | |
| SCHEMBL3144514 | 0.81 | GPR84 (0.46) | GPR84NR4A2HTR2ATRPM8IDO1 | |
| SCHEMBL29769232 | 0.77 | SLC22A6 (0.51) | GPR84NR4A2 | |
| SCHEMBL460942 | 0.77 | SLC22A6 (0.51) | GPR84NR4A2 | |
| SCHEMBL1921362 | 0.76 | CSNK2A1 (0.43) | — | |
| SCHEMBL28110298 | 0.76 | F7 (0.43) | F7F3GPR84NR4A2PYGL | |
| SCHEMBL28167760 | 0.75 | IDO1 (0.60) | F7F3GPR84NR4A2PYGL | |
| SCHEMBL305771 | 0.74 | GPR84 (0.49) | F7F3GPR84NR4A2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261435-B | Microorganism detection system and method | 3M创新有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104968778-A | Method and culture device for detecting yeasts and molds | 3M INNOVATIVE PROPERTIES CO | 2015-10-07 | — | — | CN | disclosed |
| CN-102803504-B | Detection of acid-producing bacteria | 3M INNOVATIVE PROPERTIES CO | 2015-07-01 | — | — | CN | disclosed |