Sugi Predict

Sugi Predict / Compounds / SCHEMBL2806955

SCHEMBL2806955

SCHEMBL2806955

O=C(O)c1nc2ccccc2c(C(=O)O)c1-c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.73
▸ DHODH Q02127 4/20 0.58
▸ PDE10A Q9Y233 4/20 0.58
▸ TSHR P16473 1/20 0.57
▸ SMN1; SMN2 Q16637 3/20 0.57
▸ MAPT P10636 2/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ GAA P10253 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ DYRK1A Q13627 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11381046 0.88 LMNA (0.61) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL24122754 0.84 LMNA (1.00) LMNADHODHPDE10ATSHRMAPT
SCHEMBL3743372 0.84 LMNA (0.71) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL10467734 0.83 ALDH1A1 (0.63) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL3776440 0.83 LMNA (0.69) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL2934268 0.83 LMNA (0.69) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL31109172 0.81 SMN1; SMN2 (0.55) LMNADHODHPDE10ASMN1; SMN2MAPT
SCHEMBL4954968 0.79 MAPT (0.55) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL641899 0.78 PDE10A (0.66) LMNADHODHPDE10ATSHRSMN1; SMN2
SCHEMBL29377848 0.78 PDE10A (0.66) LMNADHODHPDE10ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
JP-6016641-A — — None — — JP disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 — — EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 — — CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 — — US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 — — WO disclosed
WO-2018119500-A1 VISCOELASTIC COSMETIC COMPOSITIONS L'OREAL (FR) 2018-07-05 — — WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed
EP-0709377-B1 Process for producing quinolin-2-yl benzoic acid compounds ASAHI GLASS CO LTD (JP) 1999-09-29 — — EP disclosed
EP-0709377-A1 Process for producing quinolin-2-yl benzoic acid compounds ASAHI GLASS COMPANY LTD. (JP) 1996-05-01 — — EP disclosed
JP-H0616641-A QUINOLIN-2-YLBENZOIC ACID DERIVATIVE AND ITS PRODUCTION ASAHI GLASS CO LTD 1994-01-25 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 LMNA 1561/4885DHODH 823/4885PDE10A 2442/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB LMNA 72/4885DHODH 3231/4885PDE10A 3978/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA LMNA 833/4885DHODH 1138/4885PDE10A 1815/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA LMNA 966/4885DHODH 922/4885PDE10A 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.