Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CCND1 | P24385 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166025 | 0.79 | CDK4 (0.47) | CDK4CCND1MAPTCCNE2CCNE1 | |
| SCHEMBL27648564 | 0.78 | JAK2 (0.53) | MAPTPABPC1 | |
| SCHEMBL28177392 | 0.77 | ALDH1A1 (0.38) | CDK4CCND1MEN1MAPTKMT2A | |
| SCHEMBL28851455 | 0.76 | BTK (0.39) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL27973848 | 0.73 | IMPDH2 (0.49) | CDK4CCND1MEN1MAPTKMT2A | |
| SCHEMBL28188584 | 0.73 | POLB (0.55) | MEN1MAPTKMT2APABPC1 | |
| SCHEMBL28848039 | 0.73 | PKM (0.35) | MEN1MAPTKMT2APABPC1 | |
| SCHEMBL8967636 | 0.72 | PABPC1 (0.53) | MEN1KMT2APABPC1 | |
| SCHEMBL28165788 | 0.72 | BTK (0.41) | MEN1MAPTKMT2AAHR | |
| SCHEMBL23926188 | 0.71 | CDK4 (0.50) | CDK4CCND1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | disclosed |