Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | GLI1 | P08151 | 1/20 | 0.30 |
| ▸ | GLI2 | P10070 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.30 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.30 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.30 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166025 | 0.77 | CDK4 (0.47) | BTKCCNE2CDK4CCND1CCNE1 | |
| SCHEMBL28851457 | 0.76 | BTK (0.52) | BTKJAK2CDK2 | |
| SCHEMBL28202384 | 0.76 | MAOA (0.39) | MAOADYRK1ACDK4CCND1CDK2 | |
| SCHEMBL28166035 | 0.76 | CDK4 (0.43) | DYRK1ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL28177392 | 0.71 | ALDH1A1 (0.38) | DYRK1ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2313068 | 0.67 | KIF11 (0.48) | MAOADYRK1A | |
| SCHEMBL16320377 | 0.67 | BTK (0.54) | BTKJAK2 | |
| SCHEMBL28848039 | 0.65 | PKM (0.35) | BTK | |
| SCHEMBL28203028 | 0.62 | CDK4 (0.48) | MAOADYRK1ACCNE2CDK4CCND1 | |
| SCHEMBL2307656 | 0.62 | ALDH1A1 (0.49) | MAOADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358546-B | The tetrahydro carbazole being substituted and carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2017-10-31 | — | — | CN | disclosed |