Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.35 |
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25178588 | 0.81 | CA1 (0.37) | CA1CA2CA7CA4CA9 | |
| SCHEMBL3424155 | 0.80 | TSHR (0.35) | MEN1KMT2A | |
| SCHEMBL1280536 | 0.80 | — | — | |
| SCHEMBL27879059 | 0.80 | CA1 (0.36) | CA1CA2CA7CA4CA9 | |
| SCHEMBL28136012 | 0.79 | TDP1 (0.36) | CA1CA2CA7CA4CA9 | |
| Sulfuric Acid SCHEMBL28648726 | 0.76 | ALDH1A1 (0.45) | CA1CA2CA7CA4CA9 | |
| SCHEMBL1446275 | 0.76 | TP53 (0.33) | — | |
| Sulfuric Acid SCHEMBL1324007 | 0.76 | CA2 (0.36) | CA1CA2CA7CA4CA9 | |
| Silver SCHEMBL28388421 | 0.76 | — | — | |
| Lithium Ion SCHEMBL28643369 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290308-A | Ionic crosslinking agent and preparation method thereof, and aqueous acrylic pressure-sensitive adhesive for high-initial-adhesion high-holding-strength adhesive paper labels and preparation method thereof | 万华化学集团股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118206702-A | High-solid-content polymer emulsion and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116836657-B | Water-based optical adhesive and preparation method thereof | 广东荣鼎光学新材料科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115926041-B | Hydroxyl water dispersion with network crosslinked structure and preparation method thereof | 无锡洪汇新材料科技股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116836657-A | Water-based optical adhesive and preparation method thereof | 广东荣鼎光学新材料科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116462808-A | Fluorine-silicon emulsion for water-based varnish and preparation method thereof | 惠州市舜丰印材科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-116445105-A | Double-component efficient antibacterial aqueous acrylic acid spray adhesive and preparation method thereof | 万华化学集团股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116239975-A | Novel environment-friendly self-crosslinking aqueous laminating adhesive and preparation method thereof | 沧州冀春新材料有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-115286973-B | Water-based epoxy zinc-rich coating and preparation method and application thereof | 海洋化工研究院有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115926041-A | Network cross-linked structure hydroxyl aqueous dispersion and preparation method thereof | 无锡洪汇新材料科技股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-112574361-B | Preparation method of high-color-fastness water-based acrylate resin color paste, application and use method thereof | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-111961424-B | High-solid-content low-viscosity acrylate emulsion pressure-sensitive adhesive and preparation method and application thereof | 南京林业大学 | 2022-02-15 | — | — | CN | claimed |
| CN-113896827-A | Acrylate microemulsion and preparation method thereof | 佛山罗斯夫科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113896841-A | Amine-free acrylate waterproof emulsion and preparation method thereof | 佛山罗斯夫科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113372493-A | Preparation method and application of strippable water-based acrylate emulsion | 万华化学集团股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-113307906-A | Method for producing a high internal phase emulsion foam without hydrophilic post-treatment, foam and use thereof | 万华化学集团股份有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-112574361-A | Preparation method of high-color-fastness water-based acrylate resin color paste, application and use method thereof | 万华化学集团股份有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-111961424-A | High-solid-content low-viscosity acrylate emulsion pressure-sensitive adhesive and preparation method and application thereof | 南京林业大学 | 2020-11-20 | — | — | CN | claimed |
| CN-111484786-A | Resin for water-based ink gloss oil and preparation method thereof | 广东东方一哥新材料股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-111116831-A | Preparation method of hydroxyl acrylic emulsion | 黄禹 | 2020-05-08 | — | — | CN | claimed |