Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1280536 | 1.00 | — | — | |
| SCHEMBL27797393 | 0.94 | — | — | |
| SCHEMBL1446275 | 0.94 | TP53 (0.33) | TSHRTP53 | |
| Silver SCHEMBL28388421 | 0.94 | — | — | |
| Lithium Ion SCHEMBL28643369 | 0.94 | — | — | |
| Potassium Ion SCHEMBL28891251 | 0.94 | — | — | |
| Oxirane SCHEMBL9614183 | 0.89 | L3MBTL1 (0.36) | — | |
| Methacrylic Acid SCHEMBL27972680 | 0.83 | TGFBR1 (0.32) | — | |
| SCHEMBL28357253 | 0.80 | CA1 (0.35) | MEN1KMT2A | |
| SCHEMBL28534407 | 0.79 | TSHR (0.41) | TSHRMEN1ALDH1A1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889322-B1 | BLEND OF IONIC (CO) POLYMER RESINS AND MATRIX (CO) POLYMERS | ARKEMA INC (US) | 2013-02-20 | — | — | EP | disclosed |
| US-7815986-B2 | membrane-electrode assemblies for use in fuel cells; polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer | ARKEMA INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-7803891-B2 | Polyelectrolyte styrenic polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7781529-B2 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7629426-B2 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080242819-A1 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242805-A1 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080241630-A1 | membrane-electrode assemblies for use in fuel cells; polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242833-A1 | BLEND OF IONIC (CO)POLYMER RESINS AND MATRIX (CO)POLYMERS | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-7396880-B2 | Polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer; useful for membrane-electrode assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-20060269815-A1 | Polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer; useful for membrane-electrode assemblies for use in fuel cells | ARKEMA INC. | 2006-11-30 | — | — | US | disclosed |