Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360338 | 0.81 | MCL1 (0.46) | MEN1KMT2A | |
| SCHEMBL28364144 | 0.81 | SLC9A1 (0.41) | MEN1KMT2A | |
| SCHEMBL28360382 | 0.79 | LMNA (0.43) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL28586394 | 0.77 | KMO (0.34) | L3MBTL1MEN1KMT2A | |
| SCHEMBL28360376 | 0.76 | MCL1 (0.49) | L3MBTL1 | |
| SCHEMBL28364142 | 0.73 | RXFP1 (0.43) | MEN1KMT2A | |
| SCHEMBL28453540 | 0.70 | ESR1 (0.39) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7880056 | 0.69 | L3MBTL1 (0.50) | PLA2G10BRD4L3MBTL1 | |
| SCHEMBL28363847 | 0.68 | THRB (0.41) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL5837445 | 0.68 | KMT2A (0.47) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669046-A | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2020-01-10 | — | — | CN | disclosed |