Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360382 | 0.86 | LMNA (0.43) | L3MBTL1KDM4E | |
| SCHEMBL28364142 | 0.85 | RXFP1 (0.43) | — | |
| SCHEMBL28360338 | 0.84 | MCL1 (0.46) | MCL1 | |
| SCHEMBL28586394 | 0.79 | KMO (0.34) | L3MBTL1ALDH1A1HPGD | |
| SCHEMBL28363847 | 0.76 | THRB (0.41) | L3MBTL1KDM4E | |
| SCHEMBL28364015 | 0.76 | CNR2 (0.31) | L3MBTL1 | |
| SCHEMBL28582047 | 0.75 | MCL1 (0.48) | MCL1KRASL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28364144 | 0.73 | SLC9A1 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1096760 | 0.69 | L3MBTL1 (0.70) | MCL1KRASL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL418126 | 0.67 | MCL1 (1.00) | MCL1L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669046-A | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2020-01-10 | — | — | CN | disclosed |