Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 13/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360382 | 0.86 | LMNA (0.43) | RXFP1MEN1KMT2A | |
| SCHEMBL28360376 | 0.85 | MCL1 (0.49) | — | |
| SCHEMBL28360338 | 0.84 | MCL1 (0.46) | PHGDHMEN1KMT2A | |
| SCHEMBL28586394 | 0.79 | KMO (0.34) | RXFP1MEN1KMT2A | |
| SCHEMBL28363847 | 0.76 | THRB (0.41) | RXFP1MEN1KMT2A | |
| SCHEMBL28364015 | 0.73 | CNR2 (0.31) | MEN1KMT2A | |
| SCHEMBL28364144 | 0.73 | SLC9A1 (0.41) | MEN1KMT2A | |
| SCHEMBL28697637 | 0.71 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL28697639 | 0.70 | HPGD (0.41) | MEN1KMT2A | |
| SCHEMBL4919697 | 0.69 | L3MBTL1 (0.70) | RXFP1PHGDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669046-B | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110669046-A | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2020-01-10 | — | — | CN | disclosed |