Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.48 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.44 |
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.44 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 2/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.41 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.41 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.40 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393644 | 0.90 | FUT7 (0.48) | FUT7CA2PPARATHRBTHRA | |
| SCHEMBL11794637 | 0.84 | PPARA (0.50) | CA2PPARATHRBTHRAS1PR1 | |
| SCHEMBL11234521 | 0.84 | PPARA (0.53) | FUT7PPARAFDFT1 | |
| SCHEMBL9452161 | 0.82 | FUT7 (0.51) | FUT7CA2PPARATHRBTHRA | |
| SCHEMBL5617338 | 0.80 | FUT7 (0.46) | FUT7CA2PPARATHRBTHRA | |
| SCHEMBL5147946 | 0.78 | FUT7 (0.44) | FUT7CA2PPARATHRBTHRA | |
| SCHEMBL5320216 | 0.78 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 | |
| SCHEMBL5322295 | 0.78 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 | |
| SCHEMBL6910582 | 0.78 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 | |
| SCHEMBL8070739 | 0.78 | S1PR1 (0.51) | CA2PPARATHRBTHRAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115895040-A | Modified layered nano material and application thereof in preparation of PPR (polypropylene random copolymer) material | 联塑科技发展(贵阳)有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-113025251-B | Antistatic UV solvent-free optical adhesive, preparation method thereof and touch display screen | 广州鹿山先进材料有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-113025251-A | Antistatic UV solvent-free optical adhesive, preparation method thereof and touch display screen | 广州鹿山光电材料有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-118880546-A | Nanofiber-reinforced polyester fiber net material suitable for supporting soft rock roadway of coal mine and preparation method thereof | 中煤科工开采研究院有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118065053-A | Feather and fiber mixed filling pad and production process thereof | 顾家家居股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115895040-A | Modified layered nano material and application thereof in preparation of PPR (polypropylene random copolymer) material | 联塑科技发展(贵阳)有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115895090-A | Preparation method of conductive polymer composite material with low percolation threshold | 东南大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115216969-A | Water-based sizing agent and preparation method and application thereof | 西华大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113025251-B | Antistatic UV solvent-free optical adhesive, preparation method thereof and touch display screen | 广州鹿山先进材料有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114919147-A | Preparation process of thin shading reflection sheet for backlight module | 四川龙华光电薄膜股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114859604-A | Shading reflection film, backlight module and preparation method thereof | 四川龙华光电薄膜股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-113024929-B | Preparation method of conductive polymer composite material | 东南大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111793226-B | Antistatic super absorbent resin and preparation method and application thereof | 山东诺尔生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112961477-B | Hydrophobic material for insulin syringe and processing and forming method thereof | 普昂(杭州)医疗科技股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113024929-A | Preparation method of conductive polymer composite material | 东南大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-113025251-A | Antistatic UV solvent-free optical adhesive, preparation method thereof and touch display screen | 广州鹿山光电材料有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-112961477-A | Hydrophobic material for insulin syringe and processing and forming method thereof | 普昂(杭州)医疗科技股份有限公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-111793226-A | Antistatic super absorbent resin and preparation method and application thereof | 山东诺尔生物科技有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111472168-A | Shoes with iodine wine resisting function | 泉州宇途科技有限公司 | 2020-07-31 | — | — | CN | disclosed |