Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.47 |
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.43 |
| ▸ | THRA known ✓ | P10827 | 2/20 | 0.43 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 2/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.41 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.41 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437699 | 0.90 | FUT7 (0.49) | FUT7CA2PPARAS1PR1S1PR2 | |
| SCHEMBL8070739 | 0.85 | S1PR1 (0.51) | CA2PPARAS1PR1S1PR2S1PR3 | |
| SCHEMBL9452161 | 0.84 | FUT7 (0.51) | FUT7CA2PPARAS1PR1S1PR2 | |
| SCHEMBL11335756 | 0.83 | PPARA (0.44) | FUT7CA2PPARAS1PR1S1PR2 | |
| SCHEMBL5617338 | 0.79 | FUT7 (0.46) | FUT7CA2PPARAS1PR1S1PR2 | |
| SCHEMBL11794637 | 0.78 | PPARA (0.50) | CA2PPARAS1PR1S1PR2S1PR3 | |
| SCHEMBL5147946 | 0.77 | FUT7 (0.44) | FUT7CA2PPARAS1PR1S1PR2 | |
| SCHEMBL5322295 | 0.77 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 | |
| SCHEMBL5320216 | 0.77 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 | |
| SCHEMBL6910582 | 0.77 | FUT7 (0.72) | FUT7CA2THRBTHRASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288059-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-5153115-A | A backing or subbing antistatic layer comprising an acrylic ester, amide or ketone having ether, amine and/or sulfide groups; high-speed, automatic development protection | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5028516-A | Method of forming an image comprising rapidly developing an infrared sensitized photographic material comprising surfactants | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0401826-A1 | Silver halide photographic materials and method for manufacture thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4943520-A | SUBBING LAYER OF POLYOLS; ENDCAPPED POLYETHERS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0288059-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
| US-4358532-A | Photographic element | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| US-4336322-A | DYE RELEASING REDOX COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |