SCHEMBL5147946

SCHEMBL5147946

CCCCCCCCc1ccc(OC(C)OC(C)OC(C)S(=O)(=O)[O-])cc1.[Na+]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 3/20 0.43
THRB known ✓ P10828 3/20 0.40
THRA known ✓ P10827 2/20 0.40
ADORA3 known ✓ P0DMS8 2/20 0.37
PTGS1 known ✓ P23219 1/20 0.37
ADORA2A known ✓ P29274 1/20 0.37
PTGS2 known ✓ P35354 1/20 0.37
CA12 known ✓ O43570 1/20 0.37
CA1 known ✓ P00915 1/20 0.37
FUT7 Q11130 1/20 0.44
PPARA Q07869 1/20 0.42
S1PR1 P21453 2/20 0.38
S1PR2 O95136 1/20 0.38
S1PR3 Q99500 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
FDFT1 P37268 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
ESR1 P03372 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617338 0.97 FUT7 (0.46) FUT7CA2PPARATHRBTHRA
SCHEMBL5490693 0.86 PPARA (0.46) CA2PPARATHRBTHRAS1PR1
SCHEMBL9724545 0.84 CA2 (0.43) FUT7CA2THRBTHRAS1PR1
SCHEMBL4955024 0.84 PPARA (0.47) CA2PPARATHRBTHRAS1PR1
SCHEMBL9724546 0.82 CA2 (0.44) FUT7CA2THRBTHRAS1PR1
SCHEMBL5147949 0.82 MEN1 (0.48) FUT7CA2S1PR1S1PR2S1PR3
SCHEMBL9452161 0.80 FUT7 (0.51) FUT7CA2PPARATHRBTHRA
SCHEMBL7739699 0.79 THRA (0.42) FUT7PPARATHRBTHRAPTGS2
SCHEMBL28437699 0.78 FUT7 (0.49) FUT7CA2PPARATHRBTHRA
SCHEMBL9393644 0.77 FUT7 (0.48) FUT7CA2PPARATHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7172856-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed
EP-1365285-B1 A method for processing a silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2006-11-02 EP disclosed
CN-1261816-C Silver halide colour photographic sensitive material FUJI PHOTO FILM CO LTD (JP) 2006-06-28 CN disclosed
EP-1271241-B1 Method for processing silver halide color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2006-04-05 EP disclosed
US-7022469-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-04-04 US disclosed
US-6952294-B2 Method of reading an image, method of forming a color image, device for forming a color image, silver halide color photosensitive material, and a device for processing a photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-0743558-B1 Photographic processing composition and processing method FUJI PHOTO FILM CO LTD (JP) 2005-08-03 EP disclosed
US-6852481-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-02-08 US disclosed
US-6838231-B2 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-04 US disclosed
US-6815156-B2 HEXAGONAL TABULAR SILVER HALIDE GRAIN HAVING A SMOOTH FACE AS A PRINCIPAL PLANE, HIGH SILVER IODIDE CONTENT, PROJECTED AREA DIAMETER; EXCELLENT IN THE RATIO OF SENSITIVITY/GRANULARITY, FORMING A BLUE- SENSITIVE LAYER FUJI PHOTO FILM CO., LTD. (JP) 2004-11-09 US disclosed
EP-0280252-B1 Silver halide photographic material and method for forming super high contrast image therewith FUJI PHOTO FILM CO LTD (JP) 1994-01-12 EP disclosed
US-5260178-A Tricarbocyanine dye in atleast one hydrophilic collidal layer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed
US-5232825-A Scratch resistant, high speed processability; image quality FUJI PHOTO FILM CO., LTD. (JP) 1993-08-03 US disclosed
US-5230993-A Subbing layer having cationic polymer, ammonium or phosphonium salts; for medical use or nondestructive testing FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US disclosed
US-5190855-A Hydroxypolyazaindene Complexing Agent FUJI PHOTO FILM CO., LTD. (JP) 1993-03-02 US disclosed
EP-0476521-A2 Silver halide photographic material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 1992-03-25 EP disclosed
EP-0476535-A1 Photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-03-25 EP disclosed
US-4965180-A SUPPORT, SUBBING LAYER, AQUEOUS POLYMER LATEX FUJII PHOTO FILM CO., LTD. (JP) 1990-10-23 US disclosed
US-4965170-A REDUCIBLE, TIME-RELEASING DYE COMPOUND; NONDIFFUSING; ANTISOILANTS; ALSO INCLUDING A HIGH-CONTRAST HYDRAZINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-10-23 US disclosed
US-4942114-A FLUORESCENT, REFLECTIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed