Sugi Predict

Sugi Predict / Compounds / SCHEMBL2875340

SCHEMBL2875340

SCHEMBL2875340

N#Cc1cccc([N+](=O)[O-])c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ VCAM1 P19320 1/20 0.46
▸ TDP1 Q9NUW8 3/20 0.45
▸ GPR35 Q9HC97 2/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ HPGD P15428 2/20 0.43
▸ GRIA1 P42261 2/20 0.40
▸ GRIA2 P42262 2/20 0.40
▸ GRIA3 P42263 2/20 0.40
▸ GRIA4 P48058 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ GRM6 O15303 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ KDM4D Q6B0I6 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ POLB P06746 2/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ APEX1 P27695 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698798 0.83 TDP1 (0.47) TDP1GPR35ALDH1A1HPGDTSHR
SCHEMBL22009905 0.83 VCAM1 (0.51) VCAM1TDP1ALDH1A1HPGDGRIA1
SCHEMBL16952307 0.81 TDP1 (0.45) TDP1GPR35ALDH1A1HPGDTSHR
SCHEMBL29382907 0.80 VCAM1 (0.56) VCAM1TDP1GPR35ALDH1A1HPGD
SCHEMBL56638 0.80 VCAM1 (0.56) VCAM1TDP1GPR35ALDH1A1HPGD
SCHEMBL3010961 0.80 TDP1 (0.61) TDP1GPR35ALDH1A1TSHRSMN1; SMN2
SCHEMBL220318 0.79 VCAM1 (0.47) VCAM1TDP1GPR35ALDH1A1HPGD
SCHEMBL30694393 0.79 VCAM1 (0.47) VCAM1TDP1GPR35ALDH1A1HPGD
SCHEMBL622040 0.79 GPR35 (0.53) VCAM1TDP1GPR35ALDH1A1HPGD
Selenium SCHEMBL9501261 0.79 VCAM1 (0.55) VCAM1TDP1GPR35ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106750655-A A kind of anti-slip rubber sole 福建省惠安县万事达鞋塑有限公司 2017-05-31 — — CN claimed
EP-3947350-B1 SUBSTITUTED 2-HETEROARYL AMINOBENZENES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS BAYER AG (DE) 2026-05-27 — — EP disclosed
CN-121735780-A Preparation method of 2-fluoro-3-nitrobenzoic acid compound 内蒙古宜达化学科技有限公司 2026-03-27 — — CN disclosed
US-20250353842-A1 BICYCLIC AMINE CDK12 INHIBITORS INCYTE CORP (US) 2025-11-20 — — US disclosed
US-12466815-B2 Carboxamide compounds and uses thereof INCYTE CORPORATION (US) 2025-11-11 — — US disclosed
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF MAZE THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
US-20250311727-A1 SUBSTITUTED 2-AMINOAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-10-09 — — US disclosed
US-12415786-B2 Substituted 2-heteroarylaminobenzenes and the salts thereof and their use as herbicidal agents BAYER AKTIENGESELLSCHAFT (DE) 2025-09-16 — — US disclosed
US-20250282781-A1 APOL1 INHIBITORS AND METHODS OF USE HERCULES CAPITAL, INC., AS AGENT 2025-09-11 — — US disclosed
EP-4171567-B1 CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH CELGENE CORP (US) 2025-09-03 — — EP disclosed
WO-2009064848-A1 3-HETEROCYCLIC SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF SCHERING CORPORATION (US) 2009-05-22 — — WO disclosed
CN-100439332-C Novel thiourea derivatives and the pharmaceutical compositions containing thd same PACFIC CORP (KR) 2008-12-03 — — CN disclosed
CN-101203484-A Amide derivative and pesticide containing such compound MITSUI CHEMICALS INC (JP) 2008-06-18 — — CN disclosed
CN-1418191-A Novel thiourea derivatives and pharmaceutical compositions containing the same PACFIC CORP (KR) 2003-05-14 — — CN disclosed
EP-0593603-B1 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORP (US) 2002-11-20 — — EP disclosed
US-6127359-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 2000-10-03 — — US disclosed
US-5939412-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-08-17 — — US disclosed
US-5693636-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORPORATION (US) 1997-12-02 — — US disclosed
EP-0593603-A1 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1994-04-27 — — EP disclosed
WO-1993000095-A2 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-01-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250311727-A1 SUBSTITUTED 2-AMINOAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES DDC, WIZ, DDT VCAM1 4878/4885TDP1 3333/4885GPR35 2364/4885
US-20250353842-A1 BICYCLIC AMINE CDK12 INHIBITORS CDK12, CDK1, CDK2 VCAM1 4514/4885TDP1 1132/4885GPR35 3803/4885
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF APOL1, APOB, LDLR VCAM1 332/4885TDP1 1543/4885GPR35 3464/4885
US-12415786-B2 Substituted 2-heteroarylaminobenzenes and the salts thereof and their use as herbicidal agents GUSB, DDT, GLB1 VCAM1 4851/4885TDP1 3828/4885GPR35 3878/4885
US-20250282781-A1 APOL1 INHIBITORS AND METHODS OF USE APOL1, APOB, PON1 VCAM1 1089/4885TDP1 798/4885GPR35 4559/4885
US-12466815-B2 Carboxamide compounds and uses thereof PCK1, PHKG2, PHKG1 VCAM1 4682/4885TDP1 1427/4885GPR35 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.