Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732171 | 0.82 | TERT (0.40) | TERTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL27732170 | 0.80 | PRKCZ (0.36) | PRKCZADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL25178380 | 0.78 | MAPT (0.48) | PRKCZTERTKDM4EALDH1A1DRD3 | |
| SCHEMBL27995323 | 0.77 | TERT (0.34) | TERTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27369841 | 0.76 | ALDH1A1 (0.43) | PRKCZTERTKDM4EALDH1A1RAB9A | |
| SCHEMBL28523211 | 0.75 | KMT2A (0.47) | PRKCZTERTKDM4EALDH1A1MAPT | |
| SCHEMBL27995307 | 0.75 | TERT (0.36) | TERTSMN1; SMN2 | |
| SCHEMBL28091311 | 0.74 | HTR3E (0.40) | TERTKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28897005 | 0.73 | HSD17B10 (0.41) | TERTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL27447779 | 0.73 | CD274 (0.46) | TERTKDM4EALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920753-B | 6-fluoro-dihydropyran [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |