Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912963 | 0.89 | ALDH1A1 (0.42) | CNR1CNR2MEN1KMT2AITGA4 | |
| SCHEMBL2910598 | 0.89 | NR1H4 (0.56) | NR1H4MITFFFAR1CNR1CNR2 | |
| SCHEMBL2913374 | 0.86 | BCL2L1 (0.36) | NR1H4ITGA4L3MBTL1 | |
| SCHEMBL2913166 | 0.84 | XDH (0.38) | MEN1KMT2AITGA4L3MBTL1 | |
| SCHEMBL2915315 | 0.83 | KIF18A (0.35) | NR1H4ITGA4L3MBTL1 | |
| SCHEMBL2906969 | 0.82 | ALDH1A1 (0.36) | MEN1TP53KMT2AITGA4L3MBTL1 | |
| SCHEMBL2910190 | 0.82 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2910683 | 0.82 | ALDH1A1 (0.36) | NR1H4ITGA4L3MBTL1 | |
| SCHEMBL2913154 | 0.82 | BCL2L1 (0.35) | NR1H4CYP26A1ITGA4L3MBTL1 | |
| SCHEMBL2907832 | 0.82 | BCL2L1 (0.34) | ITGA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |