Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910755 | 0.90 | MAPT (0.38) | ALDH1A1ENPP1ENPP3ITGA4L3MBTL1 | |
| SCHEMBL2913166 | 0.88 | XDH (0.38) | ALDH1A1ITGA4L3MBTL1BCL2L1CFTR | |
| SCHEMBL2910962 | 0.85 | RAB9A (0.39) | ALDH1A1L3MBTL1LMNATSHRMAPT | |
| SCHEMBL2912963 | 0.85 | ALDH1A1 (0.42) | ALDH1A1ITGA4L3MBTL1BCL2L1CFTR | |
| SCHEMBL2906969 | 0.84 | ALDH1A1 (0.36) | ALDH1A1ITGA4L3MBTL1F10LMNA | |
| SCHEMBL2915626 | 0.84 | ITGA4 (0.34) | ALDH1A1ITGA4L3MBTL1F10GAA | |
| SCHEMBL2913446 | 0.83 | ALDH1A1 (0.36) | ALDH1A1ITGA4L3MBTL1BCL2L1CFTR | |
| SCHEMBL2915315 | 0.83 | KIF18A (0.35) | ITGA4L3MBTL1F10BCL2L1NR1H4 | |
| SCHEMBL2910190 | 0.83 | GPR27 (0.42) | — | |
| SCHEMBL2913374 | 0.83 | BCL2L1 (0.36) | ALDH1A1ITGA4L3MBTL1BCL2L1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |