Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 17/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912963 | 0.89 | ALDH1A1 (0.42) | MEN1KMT2A | |
| SCHEMBL2913166 | 0.89 | XDH (0.38) | MEN1KMT2A | |
| SCHEMBL2913446 | 0.85 | ALDH1A1 (0.36) | MEN1KMT2A | |
| SCHEMBL2907832 | 0.84 | BCL2L1 (0.34) | — | |
| SCHEMBL2913154 | 0.84 | BCL2L1 (0.35) | — | |
| SCHEMBL2915315 | 0.83 | KIF18A (0.35) | — | |
| SCHEMBL2907657 | 0.83 | MAPT (0.45) | MEN1KMT2A | |
| SCHEMBL2910683 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL2908073 | 0.82 | NR1H4 (0.47) | MEN1KMT2A | |
| SCHEMBL2910962 | 0.82 | RAB9A (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |