Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.34 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 2/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907832 | 0.90 | BCL2L1 (0.34) | BCL2L1BCL2MCL1SIRT5ITGA4 | |
| SCHEMBL2915115 | 0.90 | BCL2 (0.37) | BCL2ITGA4L3MBTL1POLBKDM4E | |
| SCHEMBL2913166 | 0.88 | XDH (0.38) | BCL2L1ITGA4L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2915315 | 0.88 | KIF18A (0.35) | BCL2L1BCL2MCL1SIRT5ITGA4 | |
| SCHEMBL2913374 | 0.84 | BCL2L1 (0.36) | BCL2L1BCL2MCL1SIRT5ITGA4 | |
| SCHEMBL2910190 | 0.84 | GPR27 (0.42) | — | |
| SCHEMBL2908230 | 0.84 | ITGA4 (0.41) | ITGA4L3MBTL1POLBALDH1A1HPGD | |
| SCHEMBL2912963 | 0.83 | ALDH1A1 (0.42) | BCL2L1BCL2ITGA4L3MBTL1ALDH1A1 | |
| SCHEMBL2910683 | 0.82 | ALDH1A1 (0.36) | BCL2L1ITGA4L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL2908073 | 0.82 | NR1H4 (0.47) | ITGA4L3MBTL1CYP26A1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |