Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 11/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909532 | 0.91 | NR1H4 (0.39) | KIF18AITGA4L3MBTL1NR1H4BCL2 | |
| SCHEMBL2907832 | 0.88 | BCL2L1 (0.34) | KIF18ABCL2L1ITGA4L3MBTL1BCL2 | |
| SCHEMBL2913154 | 0.88 | BCL2L1 (0.35) | KIF18ABCL2L1ITGA4L3MBTL1NR1H4 | |
| SCHEMBL2913166 | 0.87 | XDH (0.38) | KIF18ABCL2L1ITGA4L3MBTL1 | |
| SCHEMBL2908230 | 0.86 | ITGA4 (0.41) | ITGA4L3MBTL1POLB | |
| SCHEMBL2913374 | 0.85 | BCL2L1 (0.36) | KIF18ABCL2L1ITGA4L3MBTL1NR1H4 | |
| SCHEMBL2913787 | 0.85 | KIF18A (0.39) | KIF18ANR1H4BCL2 | |
| SCHEMBL2910190 | 0.83 | GPR27 (0.42) | — | |
| SCHEMBL2910683 | 0.83 | ALDH1A1 (0.36) | BCL2L1ITGA4L3MBTL1NR1H4F10 | |
| SCHEMBL2908073 | 0.83 | NR1H4 (0.47) | ITGA4L3MBTL1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |