Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907825 | 0.87 | ALDH1A1 (0.34) | ALDH1A1USP2MAPTMEN1KMT2A | |
| SCHEMBL2907963 | 0.87 | GLRA3 (0.38) | ALDH1A1CA1CA12CA9MEN1 | |
| SCHEMBL2912963 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2916134 | 0.79 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL2914123 | 0.78 | MEN1 (0.33) | ALDH1A1USP2MEN1KMT2A | |
| SCHEMBL2915264 | 0.78 | MAOB (0.37) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2913419 | 0.78 | ADORA2A (0.42) | ALDH1A1USP2MAPTMEN1KMT2A | |
| SCHEMBL2913166 | 0.77 | XDH (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2910683 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAPTCA1CA2CA9 | |
| SCHEMBL2908073 | 0.76 | NR1H4 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |