Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912963 | 0.81 | ALDH1A1 (0.42) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL1530647 | 0.80 | ALDH1A1 (0.42) | ADORA2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL2907963 | 0.78 | GLRA3 (0.38) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL2913556 | 0.78 | NPC1 (0.46) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL2912406 | 0.78 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2913166 | 0.77 | XDH (0.38) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL2910291 | 0.76 | CNR2 (0.38) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2908073 | 0.76 | NR1H4 (0.47) | MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL2913996 | 0.75 | CA1 (0.43) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL2906969 | 0.75 | ALDH1A1 (0.36) | RAB9AALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |