Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907963 | 0.83 | GLRA3 (0.38) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2912963 | 0.81 | ALDH1A1 (0.42) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL1530864 | 0.78 | KDM4E (0.47) | MAOBLMNAKMT2AMEN1PGR | |
| SCHEMBL2913446 | 0.78 | ALDH1A1 (0.36) | LMNAKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL2912406 | 0.78 | ALDH1A1 (0.35) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2916163 | 0.75 | CRBN (0.38) | — | |
| SCHEMBL2907837 | 0.75 | KDM4E (0.41) | LMNAKMT2AMEN1POLBKDM4E | |
| SCHEMBL2910291 | 0.74 | CNR2 (0.38) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2910962 | 0.74 | RAB9A (0.39) | LMNAKMT2AMEN1POLBKDM4E | |
| SCHEMBL2913996 | 0.74 | CA1 (0.43) | LMNAKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |