Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910962 | 0.89 | RAB9A (0.39) | ALDH1A1NPSR1NPC1LMNATP53 | |
| SCHEMBL2913166 | 0.85 | XDH (0.38) | ALDH1A1NPSR1NPC1LMNABCL2L1 | |
| SCHEMBL2910190 | 0.85 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2910683 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNABCL2L1L3MBTL1CFTR | |
| SCHEMBL1530642 | 0.82 | AURKB (0.42) | ALDH1A1NPSR1BCL2L1L3MBTL1POLB | |
| SCHEMBL2910291 | 0.81 | CNR2 (0.38) | ALDH1A1LMNABCL2L1CFTRMEN1 | |
| SCHEMBL2913374 | 0.80 | BCL2L1 (0.36) | ALDH1A1BCL2L1L3MBTL1CFTRITGA4 | |
| SCHEMBL2907832 | 0.79 | BCL2L1 (0.34) | BCL2L1L3MBTL1POLBCFTRITGA4 | |
| SCHEMBL2913154 | 0.79 | BCL2L1 (0.35) | ALDH1A1BCL2L1L3MBTL1POLBCFTR | |
| SCHEMBL2913556 | 0.79 | NPC1 (0.46) | ALDH1A1NPC1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |