Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206769 | 0.87 | CA2 (0.54) | CYP1A2TSHRHSD17B10CA2CA12 | |
| SCHEMBL29749150 | 0.87 | CA2 (0.54) | CYP1A2TSHRHSD17B10CA2CA12 | |
| SCHEMBL16604790 | 0.83 | ALOX5 (0.58) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL5254229 | 0.83 | ESR1 (0.63) | CYP1A2ESR1ESR2CYP3A4ALOX5 | |
| SCHEMBL3007563 | 0.83 | ESR1 (0.69) | CYP1A2ESR1ESR2CYP3A4CYP17A1 | |
| SCHEMBL13525455 | 0.82 | CA2 (0.50) | CYP1A2TSHRHSD17B10CA2CA12 | |
| SCHEMBL29617406 | 0.82 | CA2 (0.50) | CYP1A2TSHRHSD17B10CA2CA12 | |
| SCHEMBL19012422 | 0.82 | CA2 (0.60) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL7638685 | 0.80 | ALOX5 (0.44) | CYP1A2ESR1ESR2CYP3A4HSD17B10 | |
| SCHEMBL3039135 | 0.79 | CA2 (0.52) | CYP1A2TSHRHSD17B10CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1361759-A | 6-hydroxy-2-naphthyl carbinol and process for producing the same | MITSUBISHI CHEM CORP (JP) | 2002-07-31 | — | — | CN | claimed |
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | claimed |
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | claimed |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2019-01-24 | — | — | US | disclosed |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20150048285-A1 | Stable Free Radical Chromophores and Mixtures Thereof, Processes for Preparing the Same, Nonlinear Optic Materials, and Uses Thereof in Nonlinear Optical Applications | LIGHTWAVE LOGIC, INC. (US) | 2015-02-19 | — | — | US | disclosed |
| US-20120267583-A1 | STABLE FREE RADICAL CHROMOPHORES, PROCESSES FOR PREPARING THE SAME, NONLINEAR OPTIC MATERIALS AND USES THEREOF IN NONLINEAR OPTICAL APPLICATIONS | Lightwave Logic Inc. | 2012-10-25 | — | — | US | disclosed |
| US-20110178301-A1 | HETEROCYCLICAL CHROMOPHORE ARCHITECTURES | Lightwave Logic Inc. | 2011-07-21 | — | — | US | disclosed |
| WO-2011035842-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-03-31 | — | — | WO | disclosed |
| CN-1361759-A | 6-hydroxy-2-naphthyl carbinol and process for producing the same | MITSUBISHI CHEM CORP (JP) | 2002-07-31 | — | — | CN | disclosed |
| CN-1361759-A | 6-hydroxy-2-naphthyl carbinol and process for producing the same | MITSUBISHI CHEM CORP (JP) | 2002-07-31 | — | — | CN | disclosed |
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001054702-A1 | NOVEL COMPOUNDS | XYLOGEN AB (SE) | 2001-08-02 | — | — | WO | disclosed |
| JP-2001039912-A | 6-HYDROXY-2-NAPHTHYLCARBINOL AND ITS PRODUCTION | MITSUBISHI CHEMICALS CORP | 2001-02-13 | — | — | JP | disclosed |
| WO-2000073252-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-12-07 | — | — | WO | disclosed |
| JP-2000336054-A | PRODUCTION OF HYDROXYNAPHTHALDEHYDE | MITSUBISHI CHEMICALS CORP | 2000-12-05 | — | — | JP | disclosed |
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120267583-A1 | STABLE FREE RADICAL CHROMOPHORES, PROCESSES FOR PREPARING THE SAME, NONLINEAR OPTIC MATERIALS AND USES THEREOF IN NONLINEAR OPTICAL APPLICATIONS | PPOX, CRY1, CRY2 | CYP1A2 1618/4885ESR1 151/4885ESR2 170/4885 |
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | EPX, MPO, SERPINB1 | CYP1A2 105/4885ESR1 2883/4885ESR2 1859/4885 |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CYP1A2 2427/4885ESR1 2942/4885ESR2 4014/4885 |
| US-20110178301-A1 | HETEROCYCLICAL CHROMOPHORE ARCHITECTURES | NAP1L4, IPO4, NAP1L1 | CYP1A2 757/4885ESR1 2248/4885ESR2 3266/4885 |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | CYP1A2 105/4885ESR1 2883/4885ESR2 1859/4885 |
| US-20150048285-A1 | Stable Free Radical Chromophores and Mixtures Thereof, Processes for Preparing the Same, Nonlinear Optic Materials, and Uses Thereof in Nonlinear Optical Applications | CRY1, CRY2, PPOX | CYP1A2 1472/4885ESR1 126/4885ESR2 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.