SCHEMBL29351900

SCHEMBL29351900

CC(C)(C)Oc1ccc(C[C@@H](C=O)NC(=O)OCC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.49
▸ PTPN1 P18031 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MDM4 O15151 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ MDM2 Q00987 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30448102 1.00 CASP3 (0.49) CASP3PTPN1KMT2AMDM4TP53
SCHEMBL3039215 0.86 CASP3 (0.57) CASP3KMT2AMDM4TP53
SCHEMBL29664082 0.86 CASP3 (0.57) CASP3KMT2AMDM4TP53
SCHEMBL8355967 0.86 CASP3 (0.57) CASP3KMT2AMDM4TP53
SCHEMBL13323320 0.86 CASP3 (0.57) CASP3KMT2AMDM4TP53
SCHEMBL117946 0.85 MDM4 (0.51) CASP3PTPN1MDM4TP53MDM2
SCHEMBL29349956 0.85 MDM4 (0.51) CASP3PTPN1MDM4TP53MDM2
SCHEMBL119588 0.85 MDM4 (0.51) CASP3PTPN1MDM4TP53MDM2
SCHEMBL16075059 0.85 PTPN1 (0.49) PTPN1MDM4TP53MDM2
SCHEMBL31714182 0.85 MDM4 (0.51) CASP3PTPN1MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119951435-A Continuous flow synthesizer and application method 海南建邦制药科技有限公司 2025-05-09 — — CN claimed
CN-118105510-A Preparation and application of polypeptide self-assembled nano-drug carrier targeting cGAS-STING signal pathway 首都医科大学附属北京儿童医院 2024-05-31 — — CN claimed
CN-114539358-B Polypeptide, preparation method and application 中国科学院大连化学物理研究所 2023-09-15 — — CN claimed
CN-115894630-A Preparation method of linaclotide 四川轻化工大学 2023-04-04 — — CN claimed
CN-114539358-A Polypeptide, preparation method and application 中国科学院大连化学物理研究所 2022-05-27 — — CN claimed
CN-122028898-A Novel short-chain peptides and derivatives thereof 艾缇亚(上海)制药有限公司 2026-05-12 — — CN disclosed
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 — — US disclosed
EP-4700039-A1 PEPTIDE, AND COMPOSITION THEREOF AND USE THEREOF Winkey Technology USA Inc (US) 2026-02-25 — — EP disclosed
US-20260049103-A1 PEPTIDE, AND COMPOSITION THEREOF AND USE THEREOF WINKEY TECH USA INC (US) 2026-02-19 — — US disclosed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 — — US disclosed
WO-2025264177-A1 METHOD FOR CLEAVING PROTECTING GROUPS AND ORGANIC COMPOUNDS FROM SUPPORTS POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) 2025-12-26 — — WO disclosed
US-12503486-B2 Compound or salt thereof and preparation method and application of same ZHEJIANG PEPTITES BIOTECH CO., LTD. (CN) 2025-12-23 — — US disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 — — EP disclosed
CN-113956333-B Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-03-29 — — CN disclosed
CN-114245800-A Melanocyte regulatory peptides IDP研发制药有限公司 2022-03-25 — — CN disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 — — US disclosed
CN-114206916-A Restricted peptides 缇尔索卢森公司 2022-03-18 — — CN disclosed
CN-114195855-A Solid-phase synthesis method for polypeptide containing three pairs of disulfide bonds by introducing one pair of disulfide bonds 深圳翰宇药业股份有限公司 2022-03-18 — — CN disclosed
US-20220082553-A1 PATIENT SELECTION METHOD FOR INFLAMMATION PURDUE RESEARCH FOUNDATION 2022-03-17 — — US disclosed
CN-113956333-A Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-01-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049103-A1 PEPTIDE, AND COMPOSITION THEREOF AND USE THEREOF ARG1, ARGLU1, ARG2 CASP3 2030/4885PTPN1 1340/4885KMT2A 3031/4885
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens SCN8A, SCN9A, VIP CASP3 994/4885PTPN1 3325/4885KMT2A 1633/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 CASP3 2615/4885PTPN1 1902/4885KMT2A 3182/4885
US-12503486-B2 Compound or salt thereof and preparation method and application of same SEM1, REN, SETDB1 CASP3 4261/4885PTPN1 2024/4885KMT2A 431/4885
US-20220082553-A1 PATIENT SELECTION METHOD FOR INFLAMMATION FOLH1, FOLR2, TNF CASP3 1091/4885PTPN1 4474/4885KMT2A 4103/4885
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VIP, MLEC, SEC16A CASP3 1344/4885PTPN1 4052/4885KMT2A 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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