Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 known ✓ | P47900 | 3/20 | 0.55 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.55 |
| ▸ | P2RY4 known ✓ | P51582 | 11/20 | 0.48 |
| ▸ | P2RY2 known ✓ | P41231 | 8/20 | 0.48 |
| ▸ | P2RY12 known ✓ | Q9H244 | 6/20 | 0.46 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341554 | 1.00 | P2RY1 (0.55) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL8947711 | 0.86 | MAPK1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL7740603 | 0.86 | MEN1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL30887179 | 0.86 | MEN1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL15452097 | 0.84 | CXCR2 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL11932628 | 0.82 | MAPT (0.43) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL13316757 | 0.82 | MAPT (0.48) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL25851919 | 0.81 | MAPK1 (0.53) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL20043780 | 0.81 | MAPK1 (0.42) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL15448839 | 0.81 | SMN1; SMN2 (0.44) | P2RY1MEN1NSD2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4701618-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-4701617-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-3723864-B1 | THICKENED ONE-COMPONENT HAIR TONER | HENKEL AG & CO KGAA (DE) | 2026-01-14 | — | — | EP | claimed |
| EP-4398865-B1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | OREAL (FR) | 2025-10-29 | — | — | EP | claimed |
| WO-2025202160-A1 | CLEANING COMPOSITIONS COMPRISING UV LIGHT STABILIZERS | BASF SE (DE) | 2025-10-02 | — | — | WO | claimed |
| WO-2025149345-A1 | LAUNDRY DETERGENT PRODUCT | UNILEVER IP HOLDINGS B.V. (NL) | 2025-07-17 | — | — | WO | claimed |
| CN-114134731-B | Direct-injection acid dye digital printing ink and application thereof | 苏州大学 | 2025-04-25 | — | — | CN | claimed |
| EP-3873402-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3873416-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| US-20240390247-A1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | L'OREAL (FR) | 2024-11-28 | — | — | US | claimed |
| EP-3836893-B1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN OLIGOALKYLSILOXANE AND A DYEING COMPOUND | HENKEL AG & CO KGAA (DE) | 2022-09-14 | — | — | EP | claimed |
| CN-114981395-A | Laundry detergent product | 联合利华知识产权控股有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | HENKEL AG & CO. KGAA (DE) | 2022-07-12 | — | — | US | claimed |
| EP-4017953-A1 | DETERGENT SOLID COMPOSITION | Unilever IP Holdings B.V. (NL) | 2022-06-29 | — | — | EP | claimed |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | HENKEL AG & CO. KGAA (DE) | 2022-05-17 | — | — | US | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| CN-114341325-A | Solid detergent composition | 联合利华知识产权控股有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | HENKEL AG & CO. KGAA (DE) | 2022-04-05 | — | — | US | claimed |
| CN-114222555-A | Additives for colorants and methods of use thereof | 生活实验公司 | 2022-03-22 | — | — | CN | claimed |
| CN-114134731-A | Direct-injection acid dye digital printing ink and application thereof | 苏州大学 | 2022-03-04 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | KRT18, MKI67, DSG1 | P2RY1 4876/4885THRB 4573/4885P2RY4 4874/4885 |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | KRT18, MKI67, PCNA | P2RY1 4734/4885THRB 4768/4885P2RY4 4681/4885 |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | KRT18, DSG1, CUTA | P2RY1 4864/4885THRB 2660/4885P2RY4 4866/4885 |
| US-20240390247-A1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | KRT18, CUTA, MARK1 | P2RY1 4406/4885THRB 2470/4885P2RY4 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.