Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 known ✓ | P47900 | 3/20 | 0.55 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.55 |
| ▸ | P2RY4 known ✓ | P51582 | 11/20 | 0.48 |
| ▸ | P2RY2 known ✓ | P41231 | 8/20 | 0.48 |
| ▸ | P2RY12 known ✓ | Q9H244 | 6/20 | 0.46 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356228 | 1.00 | P2RY1 (0.55) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL30887179 | 0.86 | MEN1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL7740603 | 0.86 | MEN1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL8947711 | 0.86 | MAPK1 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL15452097 | 0.84 | CXCR2 (0.46) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL11932628 | 0.82 | MAPT (0.43) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL13316757 | 0.82 | MAPT (0.48) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL20043780 | 0.81 | MAPK1 (0.42) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL15448839 | 0.81 | SMN1; SMN2 (0.44) | P2RY1MEN1NSD2ALDH1A1POLB | |
| SCHEMBL25851919 | 0.81 | MAPK1 (0.53) | P2RY1MEN1NSD2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826540-B1 | Activated carbon based composition to sequester flue gas mercury in concrete | ALBEMARLE CORP (US) | 2018-05-09 | — | — | EP | claimed |
| EP-2688658-B1 | METHOD TO SEQUESTER FLUE GAS MERCURY IN CONCRETE | ALBEMARLE CORP (US) | 2016-10-12 | — | — | EP | claimed |
| EP-2099550-B1 | METHOD TO SEQUESTER FLUE GAS MERCURY IN CONCRETE | ALBEMARLE CORP (US) | 2014-11-19 | — | — | EP | claimed |
| EP-4416254-A1 | COMPOSITION | Paui AB (SE) | 2024-08-21 | — | — | EP | disclosed |
| CN-116657416-B | Environment-friendly dyeing process for cotton and linen textile | 宁波泓萌新材料科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-116657416-A | Environment-friendly dyeing process for cotton and linen textile | 昆明成先酞纺织有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023063867-A1 | COMPOSITION | PAUI AB (SE) | 2023-04-20 | — | — | WO | disclosed |
| EP-2710996-B1 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2022-07-12 | — | — | US | disclosed |
| US-20210115489-A1 | NOVEL MEDIATOR | KIKKOMAN CORPORATION (JP) | 2021-04-22 | — | — | US | disclosed |
| CN-112522148-A | Method for culturing high-performance composite flora by using printing and dyeing wastewater | 江南大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-1842319-A | Dye composition and method for examining tooth demineralization damage | PROCTER & GAMBLE (US) | 2006-10-04 | — | — | CN | disclosed |
| WO-2005087908-A1 | BLEACH ACTIVATORS AND METHOD FOR THE PRODUCTION THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-09-22 | — | — | WO | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
| US-20050058602-A1 | Dye composition and method for detection of demineralized lesions in teeth | THE PROCTER & GAMBLE COMPANY | 2005-03-17 | — | — | US | disclosed |
| WO-2003089559-A1 | BLUE COLORED LIQUID CRYSTAL COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2003-10-30 | — | — | WO | disclosed |
| US-6475975-B1 | Blue colored liquid crystal compositions | COLGATE-PALMOLIVE COMPANY | 2002-11-05 | — | — | US | disclosed |
| US-5385842-A | Anthraquinones as inhibitors of sulfide production from sulfate-reducing bacteria | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0525073-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. | DU PONT (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991015954-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115489-A1 | NOVEL MEDIATOR | MPO, EPX, LPO | P2RY1 2661/4885THRB 4364/4885P2RY4 1946/4885 |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | P2RY1 701/4885THRB 972/4885P2RY4 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.