Diamocaine

Diamocaine

SCHEMBL29358950

CCN(CC)CCOC1(c2ccccc2)CCN(CCNc2ccccc2)CC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD3 P35462 2/20 0.53
▸ CHRM2 P08172 6/20 0.44
▸ CHRM1 P11229 5/20 0.44
▸ OPRM1 P35372 2/20 0.42
▸ OPRD1 P41143 2/20 0.42
▸ OPRK1 P41145 2/20 0.42
▸ OPRL1 P41146 2/20 0.42
▸ PRCP P42785 2/20 0.39
▸ SIGMAR1 Q99720 2/20 0.39
▸ ALDH1A1 P00352 4/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 2/20 0.36
▸ CYP2D6 P10635 2/20 0.36
▸ TSHR P16473 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ SLC22A1 O15245 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diamocaine SCHEMBL592685 0.85 DRD3 (0.42) DRD3CHRM2CHRM1OPRM1PRCP
SCHEMBL11454802 0.74 HTR7 (0.52) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL11447147 0.70 OPRM1 (0.46) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL11685046 0.70 OPRM1 (0.60) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL11446493 0.69 OPRM1 (0.45) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL19475380 0.69 OPRM1 (0.66) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL7737516 0.68 HTR7 (0.58) DRD3ALDH1A1POLBCARM1PRMT6
SCHEMBL11446213 0.68 DRD3 (0.41) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL11682701 0.68 OPRM1 (0.57) DRD3OPRM1OPRD1OPRK1OPRL1
SCHEMBL473377 0.67 DRD4 (0.52) SIGMAR1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863708-B1 MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING BATTELLE MEMORIAL INSTITUTE (US) 2024-09-11 — — EP claimed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 — — US claimed
US-11633587-B2 Mixed ionic electronic conductors: devices, systems and methods of use BATTELLE MEMORIAL INSTITUTE (US) 2023-04-25 — — US claimed
US-12605332-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-04-21 — — US disclosed
EP-4683613-A1 METHOD FOR PREPARING A STERILE HYDROGEL COMPRISING A CROSS-LINKED OR NON-CROSSLINKED POLYSACCHARIDE OR A MIXTURE THEREOF Teoxane SA (CH) 2026-01-28 — — EP disclosed
EP-4683614-A1 METHOD FOR PREPARING A STERILE HYDROGEL COMPRISING A CROSS-LINKED OR NON-CROSSLINKED POLYSACCHARIDE OR A MIXTURE THEREOF Teoxane SA (CH) 2026-01-28 — — EP disclosed
US-12491207-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability VANELTIX PHARMA, INC. (US) 2025-12-09 — — US disclosed
US-12478612-B2 Deuterated domperidone compositions, methods, and preparation CINDOME PHARMA, INC. (US) 2025-11-25 — — US disclosed
US-12478582-B2 Method for incorporating organic compounds in solution within a hydrogel LABORATOIRES VIVACY (FR) 2025-11-25 — — US disclosed
US-12478576-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2025-11-25 — — US disclosed
EP-4349414-B1 FORMULATIONS FOR TRANSDERMAL ADMINISTRATION DYVE BIOSCIENCES INC (US) 2025-10-15 — — EP disclosed
US-11305106-B2 Mixed ionic electronic conductors: devices, systems and methods of use BATTELLE MEMORIAL INSTITUTE (US) 2022-04-19 — — US disclosed
US-20220105062-A1 TRANSDERMAL PENETRANT FORMULATIONS DYVE BIOSCIENCES, INC. 2022-04-07 — — US disclosed
US-20220080187-A1 Mixed Ionic Electronic Conductors: Devices, Systems and Methods of Use BATTELLE MEMORIAL INSTITUTE 2022-03-17 — — US disclosed
WO-2022053875-A1 HYDROGEL COMPRISING A CROSSLINKED AND SILYLATED POLYSACCHARIDE AND PROCESS FOR OBTAINING SAME Teoxane SA (CH) 2022-03-17 — — WO disclosed
US-20220062329-A1 METHOD OF ADMINISTRATION AND TREATMENT DYVE BIOSCIENCES, INC. 2022-03-03 — — US disclosed
US-20220047624-A1 METHOD OF ADMINISTRATION AND TREATMENT DYVE BIOSCIENCES, INC. 2022-02-17 — — US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 — — US disclosed
US-20220040225-A1 METHOD OF ADMINISTRATION AND TREATMENT DYVE BIOSCIENCES, INC. 2022-02-10 — — US disclosed
US-20220023336-A1 METHOD OF ADMINISTRATION AND TREATMENT DYVE BIOSCIENCES, INC. 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12491207-B2 Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability OGFR, ALOX5, PTGS1 DRD3 2578/4885CHRM2 2397/4885CHRM1 2318/4885
US-12605332-B2 Transdermal delivery formulations NOS1, NOS2, VDR DRD3 152/4885CHRM2 825/4885CHRM1 653/4885
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 DRD3 2578/4885CHRM2 2397/4885CHRM1 2318/4885
US-12478612-B2 Deuterated domperidone compositions, methods, and preparation DRD2, DRD1, DRD4 DRD3 4/4885CHRM2 752/4885CHRM1 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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