Diamocaine

Diamocaine

SCHEMBL592685

CCN(CC)CCOC1(c2ccccc2)CCN(CCNc2ccccc2)CC1.O=S(=O)(O)NC1CCCCC1.O=S(=O)(O)NC1CCCCC1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD3 P35462 2/20 0.42
▸ CHRM2 P08172 7/20 0.38
▸ CHRM1 P11229 6/20 0.38
▸ CYP3A4 P08684 4/20 0.38
▸ CYP2D6 P10635 3/20 0.38
▸ TSHR P16473 3/20 0.38
▸ LMNA P02545 2/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ OPRM1 P35372 2/20 0.38
▸ HTR1A P08908 1/20 0.38
▸ ADRA2A P08913 1/20 0.38
▸ DRD1 P21728 1/20 0.38
▸ SLC6A2 P23975 1/20 0.38
▸ ADRA1A P35348 1/20 0.38
▸ SLC6A3 Q01959 1/20 0.38
▸ KCNH2 Q12809 1/20 0.38
▸ PRCP P42785 2/20 0.36
▸ SIGMAR1 Q99720 2/20 0.36
▸ ACHE P22303 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diamocaine SCHEMBL29358950 0.85 DRD3 (0.53) DRD3CHRM2CHRM1CYP3A4CYP2D6
SCHEMBL11454802 0.66 HTR7 (0.52) DRD3OPRM1
Cyclamic Acid SCHEMBL11541886 0.64 KMT2A (0.49) TSHRLMNAALDH1A1POLBHTT
SCHEMBL11447147 0.63 OPRM1 (0.46) DRD3OPRM1HTR1AADRA1A
SCHEMBL11446493 0.62 OPRM1 (0.45) DRD3OPRM1ADRA1A
SCHEMBL11446213 0.62 DRD3 (0.41) DRD3CYP1A2OPRM1HTR1AADRA1A
Hydrochloric Acid SCHEMBL11505628 0.61 EPHX1 (0.49) TSHRLMNAALDH1A1POLBKDM4E
Cyclamic Acid SCHEMBL7551565 0.61 ALDH1A1 (0.47) CYP3A4CYP2D6LMNACYP1A2ACHE
Cyclamic Acid SCHEMBL7091544 0.60 L3MBTL1 (0.40) TSHRALDH1A1POLB
Piminodine SCHEMBL1286844 0.60 KCNA3 (0.66) LMNAOPRM1ADRA1AKCNH2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 — — US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 — — US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 — — US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-12605333-B2 Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release TRIS PHARMA, INC. (US) 2026-04-21 — — US disclosed
US-12605332-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-04-21 — — US disclosed
US-20260096986-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A FLOATING INTERPENETRATING POLYMER NETWORK FORMING SYSTEM TRIS PHARMA INC (US) 2026-04-09 — — US disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 — — EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-12514818-B2 Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system TRIS PHARMA, INC. (US) 2026-01-06 — — US disclosed
US-12478576-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2025-11-25 — — US disclosed
US-20030104041-A1 Transdermal and topical administration of drugs using basic permeation enhancers DERMATRENDS, INC. 2003-06-05 — — US disclosed
US-20030059471-A1 Oral delivery formulation COMPTON BRUCE JON (US) 2003-03-27 — — US disclosed
US-20020197284-A1 Transdermal and topical administration of local anesthetic agents using basic enhancers TECHNOLOGY RECOVERY SYSTEMS, LLC 2002-12-26 — — US disclosed
US-20010002404-A1 Fatty acid-pharmaceutical agent conjugates LUITPOLD PHARMACEUTICALS, INC. 2001-05-31 — — US disclosed
WO-1999030690-A1 ORAL DELIVERY FORMULATION AXIA THERAPEUTICS, INC. (US) 1999-06-24 — — WO disclosed
EP-0909183-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES Neuromedica, Inc. (US) 1999-04-21 — — EP disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 — — US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260096986-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A FLOATING INTERPENETRATING POLYMER NETWORK FORMING SYSTEM SI, FABP2, FABP6 DRD3 3065/4885CHRM2 1621/4885CHRM1 1453/4885
US-12605333-B2 Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release SI, GRPR, FABP2 DRD3 3336/4885CHRM2 3230/4885CHRM1 2722/4885
US-20010002404-A1 Fatty acid-pharmaceutical agent conjugates FABP7, FFAR2, FFAR4 DRD3 2441/4885CHRM2 2104/4885CHRM1 3136/4885
US-12605332-B2 Transdermal delivery formulations NOS1, NOS2, VDR DRD3 152/4885CHRM2 825/4885CHRM1 653/4885
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A DRD3 946/4885CHRM2 158/4885CHRM1 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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