Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 3/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584418 | 0.93 | APEX1 (0.75) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL11670702 | 0.93 | APEX1 (0.75) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL12994564 | 0.87 | ENPP2 (0.82) | APEX1ENPP2MEN1KMT2AAMY1A | |
| Ammonia Solution, Strong SCHEMBL21700410 | 0.86 | ENPP2 (0.81) | APEX1ENPP2MEN1KMT2AAMY1A | |
| SCHEMBL11670477 | 0.84 | APEX1 (1.00) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL29623460 | 0.84 | APEX1 (1.00) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL11765358 | 0.84 | ENPP2 (0.64) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL15113011 | 0.81 | ENPP2 (0.68) | APEX1ENPP2MEN1KMT2AAMY1A | |
| SCHEMBL29378215 | 0.81 | APEX1 (1.00) | APEX1ENPP2PTPN1USP2ATM | |
| SCHEMBL10891071 | 0.79 | ENPP2 (0.85) | APEX1ENPP2PRMT1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120665-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | LIFE TECHNOLOGIES CORP (US) | 2023-04-20 | — | — | US | claimed |
| CN-111977873-B | Method for using photoactivated sepiolite Si-OH for adsorption and photodegradation of water-soluble organic pollutants | 湖南工程学院 | 2023-04-07 | — | — | CN | claimed |
| US-20220291566-A1 | COLOURED OR BLACK PARTICLES | E INK CORPORATION (US) | 2022-09-15 | — | — | US | claimed |
| EP-3980140-A2 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | FRS Group, LLC (US) | 2022-04-13 | — | — | EP | claimed |
| EP-4547208-B1 | PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES | OREAL (FR) | 2026-05-27 | — | — | EP | disclosed |
| CN-122094656-A | Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition | — | 2026-05-26 | — | — | CN | disclosed |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | L'OREAL (FR) | 2026-05-26 | — | — | US | disclosed |
| US-12629555-B2 | Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same | PERIMETER SOLUTIONS, LP (US) | 2026-05-19 | — | — | US | disclosed |
| CN-122029488-A | Photosensitive coloring composition, cured product, partition wall, organic electroluminescent element, color filter, and image display device | 三菱化学株式会社 | 2026-05-12 | — | — | CN | disclosed |
| EP-4731312-A1 | SYSTEMS, APPARATUS, AND METHODS FOR DILUTION AND EFFECTIVE MIXING OF HIGH VISCOSITY LONG-TERM FIRE RETARDANT LIQUID CONCENTRATES | Perimeter Solutions LP (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2026039882-A1 | METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR | L'OREAL (FR) | 2026-02-26 | — | — | WO | disclosed |
| EP-4692146-A1 | LEVELING AGENT, RESIST COMPOSITION, AND POLARIZING PLATE | DIC Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| CN-114270263-A | Photosensitive coloring composition, cured product, image display device, and pigment dispersion liquid for image display device | 三菱化学株式会社 | 2022-04-01 | — | — | CN | disclosed |
| WO-2022059492-A1 | SILICONE CHAIN-CONTAINING POLYMER AND COATING COMPOSITION CONTAINING SAID POLYMER | DIC株式会社 | 2022-03-24 | — | — | WO | disclosed |
| CN-114193764-A | Material for three-dimensional molding, three-dimensional object, and printing method therefor | 珠海赛纳三维科技有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20220080242-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2022-03-17 | — | — | US | disclosed |
| WO-2022050062-A1 | POLYMER, COATING COMPOSITION, RESIST COMPOSITION, AND ARTICLE | DIC株式会社 | 2022-03-10 | — | — | WO | disclosed |
| US-20220072355-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2022-03-10 | — | — | US | disclosed |
| CN-114032215-A | Hybridoma cell strain secreting red 2G monoclonal antibody and application thereof | 江南大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-113993922-A | Photosensitive colored resin composition, cured product, partition wall, and image display device | 三菱化学株式会社 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629555-B2 | Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same | SLC6A12, SLC9A2, SLC11A2 | THRB 1787/4885APEX1 2662/4885ENPP2 4777/4885 |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | KRT18, CYC1, CYBA | THRB 1477/4885APEX1 989/4885ENPP2 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.