Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376241 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL31289323 | 0.75 | SLC9A1 (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL5393 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL16879491 | 0.75 | ALDH1A1 (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL1226224 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL25400045 | 0.75 | FAAH (0.39) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL8256698 | 0.75 | SLC9A1 (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL537916 | 0.75 | FAAH (0.42) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL19957621 | 0.75 | TUBB4A (0.41) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| Water SCHEMBL1042885 | 0.73 | POLB (0.48) | FAAHMGLLTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114186813-A | Two-shift inverted multi-task scheduling optimization method considering switching time | 西北工业大学 | 2022-03-15 | — | — | CN | claimed |
| US-20250327042-A1 | NOVEL P450-BM3 VARIANTS WITH IMPROVED ACTIVITY | CODEXIS INC (US) | 2025-10-23 | — | — | US | disclosed |
| CN-119968243-A | High conductivity aluminum alloy | EOS有限公司电镀光纤系统 | 2025-05-09 | — | — | CN | disclosed |
| CN-119143758-A | Preparation method of urea type HATU | 安徽昊帆生物有限公司 | 2024-12-17 | — | — | CN | disclosed |
| EP-4399285-A2 | NUCLEIC ACID POLYMERASE AND ITS USE IN PRODUCING NON-DNA NUCLEOTIDE POLYMERS | United Kingdom Research and Innovation (GB) | 2024-07-17 | — | — | EP | disclosed |
| CN-114182191-B | Thermal barrier coating and preparation method thereof | 上海电气燃气轮机有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20230332126-A1 | Botulinum Neurotoxin Proteins and Methods to Engineer and Generate Same | UNIV CALIFORNIA (US) | 2023-10-19 | — | — | US | disclosed |
| CN-111125080-B | Multi-source remote sensing image integrated management system and method based on pattern spot model | 北京航天世景信息技术有限公司 | 2023-09-26 | — | — | CN | disclosed |
| EP-4204437-A1 | BOTULINUM NEUROTOXIN PROTEINS AND METHODS TO ENGINEER AND GENERATE SAME | The Regents of the University of California (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-116256295-A | Quantitative evaluation method for quick injury of loose sandstone reservoir | 西南石油大学 | 2023-06-13 | — | — | CN | disclosed |
| WO-2023036779-A2 | NUCLEIC ACID POLYMERASES | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-03-16 | — | — | WO | disclosed |
| CN-114186813-A | Two-shift inverted multi-task scheduling optimization method considering switching time | 西北工业大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-114182191-A | Thermal barrier coating and preparation method thereof | 上海电气燃气轮机有限公司 | 2022-03-15 | — | — | CN | disclosed |
| WO-2022046768-A1 | BOTULINUM NEUROTOXIN PROTEINS AND METHODS TO ENGINEER AND GENERATE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-03 | — | — | WO | disclosed |