Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | PDE6A | P16499 | 1/20 | 0.40 |
| ▸ | PDE6G | P18545 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE6B | P35913 | 1/20 | 0.40 |
| ▸ | PDE6C | P51160 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376241 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL31289323 | 0.75 | SLC9A1 (0.50) | FAAHMGLLPDE2ATUBB4ATUBB | |
| SCHEMBL5393 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL19957621 | 0.75 | TUBB4A (0.41) | FAAHMGLLPDE4BPDE2APDE6D | |
| SCHEMBL8256698 | 0.75 | SLC9A1 (0.50) | FAAHMGLLPDE2ATUBB4ATUBB | |
| SCHEMBL25400045 | 0.75 | FAAH (0.39) | FAAHMGLLPDE4BPDE2APDE6D | |
| SCHEMBL16879491 | 0.75 | ALDH1A1 (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| SCHEMBL1226224 | 0.75 | POLB (0.50) | FAAHMGLLTUBB4ATUBBTUBA3C | |
| Potassium Ion SCHEMBL29403001 | 0.75 | FAAH (0.39) | FAAHMGLLPDE4BPDE2APDE6D | |
| SCHEMBL3605357 | 0.75 | PARP1 (0.39) | PDE4BPDE2APDE6DPDE8APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279236-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-01-06 | — | — | EP | claimed |
| US-9556149-B2 | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-HT2A serotonin receptor | ARENA PHARMACEUTICALS, INC. (US) | 2017-01-31 | — | — | US | claimed |
| US-20150045372-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLE DERIVATIVES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR | ARENA PHARMACEUTICALS, INC. | 2015-02-12 | — | — | US | claimed |
| US-8946438-B2 | Benzamides, production thereof, and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-03 | — | — | US | claimed |
| US-20140187539-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-03 | — | — | US | claimed |
| US-8735579-B2 | Benzamides, production thereof, and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-27 | — | — | US | claimed |
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | claimed |
| US-20130079518-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | LINZ GUENTER (DE) | 2013-03-28 | — | — | US | claimed |
| US-8372974-B2 | Regioselective preparation of substituted pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-12 | — | — | US | claimed |
| US-20120108572-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-03 | — | — | US | claimed |
| US-20110060141-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-10 | — | — | US | claimed |
| US-20110021538-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLE DERIVATIVES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-27 | — | — | US | claimed |
| EP-2268621-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | Boehringer Ingelheim International GmbH (DE) | 2011-01-05 | — | — | EP | claimed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| WO-2009115583-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-24 | — | — | WO | claimed |
| US-20240217929-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | CYBIN UK LTD (GB) | 2024-07-04 | — | — | US | disclosed |
| CN-111479819-B | Method for preparing peptide and method for treating alkali | 中外制药株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-20040033939-A1 | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2004-02-19 | — | — | US | disclosed |
| US-20030130173-A1 | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2003-07-10 | — | — | US | disclosed |
| WO-2003031449-A2 | CROSS-LINKED GLYCOPEPTIDE-CEPHALOSPORIN ANTIBIOTICS | THERAVANCE, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040033939-A1 | Cross-linked glycopeptide-cephalosporin antibiotics | CSGALNACT1, GYPA, ST3GAL3 | FAAH 4825/4885MGLL 2644/4885PDE4B 3590/4885 |
| US-20150045372-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLE DERIVATIVES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR | HTR5A, HTR2A, HTR3A | FAAH 1318/4885MGLL 3829/4885PDE4B 392/4885 |
| US-20140187539-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | HRH2, HRH1, HRH4 | FAAH 249/4885MGLL 2692/4885PDE4B 667/4885 |
| US-20240217929-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | TPH2, TPH1, HTR2C | FAAH 52/4885MGLL 1524/4885PDE4B 1384/4885 |
| US-20030130173-A1 | Cross-linked glycopeptide-cephalosporin antibiotics | CSGALNACT1, GYPA, ST3GAL3 | FAAH 4825/4885MGLL 2644/4885PDE4B 3590/4885 |
| US-20110060141-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | TYMS, DPYD, TYMP | FAAH 4345/4885MGLL 4805/4885PDE4B 1602/4885 |
| US-20120108572-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | HRH2, HRH1, HRH4 | FAAH 249/4885MGLL 2692/4885PDE4B 667/4885 |
| US-20130079518-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | TYMS, DPYD, TYMP | FAAH 4400/4885MGLL 4814/4885PDE4B 1860/4885 |
| US-20110021538-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLE DERIVATIVES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR | HTR5A, HTR2A, HTR3A | FAAH 1318/4885MGLL 3829/4885PDE4B 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.