Alsactide

Alsactide

SCHEMBL29406207

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCCCCN)C(C)C

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.74
▸ MC4R P32245 3/20 0.74
▸ MC5R P33032 2/20 0.74
▸ MC3R P41968 2/20 0.74
▸ MC1R Q01726 2/20 0.74
▸ CTSL P07711 3/20 0.66
▸ CTSS P25774 3/20 0.66
▸ CTSK P43235 3/20 0.66
▸ CTSH P09668 1/20 0.66
▸ GLP1R P43220 4/20 0.65
▸ CXCR4 P61073 2/20 0.63
▸ GCGR P47871 3/20 0.62
▸ CXCL8 P10145 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Giractide SCHEMBL29387618 0.96 MC4R (0.75) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL18388638 0.96 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29973172 0.95 C5AR1 (0.77) C5AR1MC4RMC5RMC3RMC1R
Codactide SCHEMBL29409825 0.95 MC4R (0.74) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29358645 0.95 MC4R (0.82) C5AR1MC4RMC5RMC3RMC1R
Intermedine SCHEMBL20548027 0.95 MC4R (0.82) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29534172 0.95 MC4R (0.78) C5AR1MC4RMC5RMC3RMC1R
Intermedine SCHEMBL22076809 0.95 MC4R (0.82) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL30017682 0.95 C5AR1 (0.77) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29533733 0.94 MC4R (0.78) C5AR1MC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115663926-A Light storage frequency modulation control method, system, equipment and medium of photovoltaic virtual synchronous machine 广东能源集团科学技术研究院有限公司 2023-01-31 — — CN claimed
CN-114414151-A Synchronous operation type energy metering device with built-in gateway and Internet of things system 成都秦川物联网科技股份有限公司 2022-04-29 — — CN claimed
CN-122094704-A Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material — 2026-05-26 — — CN disclosed
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES STELLULAR BIO, INC. (US) 2026-05-07 — — US disclosed
EP-4646217-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES Stellular Bio, Inc. (US) 2025-11-12 — — EP disclosed
US-20250186558-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF ACTIVE AGENTS ENTERA BIO LTD. (IL) 2025-06-12 — — US disclosed
WO-2025046589-A1 FORMULATIONS COMPRISING A COMBINATION OF ACID-NEUTRALIZING POLYMERIC AND NON-POLYMERIC SUBSTANCES FOR ORAL ADMINISTRATION OF ACTIVE AGENTS ENTERA BIO LTD. (IL) 2025-03-06 — — WO disclosed
WO-2025046590-A1 FORMULATIONS FOR ORAL ADMINISTRATION OF ACTIVE AGENTS ENTERA BIO LTD. (IL) 2025-03-06 — — WO disclosed
US-20250051830-A1 MEMBRANE-EMBEDDED NANOPORE AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2025-02-13 — — US disclosed
EP-4482507-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF ACTIVE AGENTS Entera Bio Ltd. (IL) 2025-01-01 — — EP disclosed
WO-2024148315-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES STELLULAR BIO, INC. (US) 2024-07-11 — — WO disclosed
WO-2023064805-A1 MEMBRANE-EMBEDDED NANOPORE AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-04-20 — — WO disclosed
US-20230102999-A1 DEUTERATED NICLOSAMIDE FIRST WAVE BIO, INC. 2023-03-30 — — US disclosed
EP-4149497-A1 NOVEL ANUCLEATED CELLS AS A SOURCE FOR TREATMENT OF PLATELET RICH PLASMA DEPENDENT DISORDERS Platelet Biogenesis, Inc. (US) 2023-03-22 — — EP disclosed
US-20230077811-A1 ACTIVATION OF NEUROPEPTIDE RECEPTORS ON PLASMACYTOID DENDRITIC CELLS TO TREAT OR PREVENT OCULAR DISEASES ASSOCIATED WITH NEOVASCULARIZATION AND INFLAMMATION TRUSTEES OF TUFTS COLLEGE 2023-03-16 — — US disclosed
EP-4125947-A1 NOVEL ANUCLEATED CELLS FOR THE TREATMENT OF DISEASES Platelet Biogenesis, Inc. (US) 2023-02-08 — — EP disclosed
US-11564896-B2 Methods of treatment FIRST WAVE BIO, INC. (US) 2023-01-31 — — US disclosed
EP-4045480-A1 PHARMACEUTICAL FORMULATIONS First Wave Bio, Inc. (US) 2022-08-24 — — EP disclosed
US-20220105057-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-04-07 — — US disclosed
US-20220079897-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220079897-A1 METHODS OF TREATMENT ACE2, ACE, SI C5AR1 2999/4885MC4R 2077/4885MC5R 2679/4885
US-11564896-B2 Methods of treatment ACE2, ACE, SI C5AR1 3213/4885MC4R 1888/4885MC5R 2483/4885
US-20250186558-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF ACTIVE AGENTS ASAH2, SLC10A2, FABP2 C5AR1 2220/4885MC4R 1851/4885MC5R 1480/4885
US-20220105057-A1 METHODS OF TREATMENT ACE2, ACE, SI C5AR1 3213/4885MC4R 1888/4885MC5R 2483/4885
US-20230102999-A1 DEUTERATED NICLOSAMIDE FH, IDH2, ECHS1 C5AR1 4521/4885MC4R 2181/4885MC5R 2290/4885
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES MYH10, PDGFA, MPL C5AR1 1839/4885MC4R 746/4885MC5R 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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