SCHEMBL29461985

SCHEMBL29461985

N=C(N)NCCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.58
TUBB P07437 2/20 0.58
TUBA3C P0DPH7 2/20 0.58
TUBA1B P68363 2/20 0.58
TUBA4A P68366 2/20 0.58
TUBB4B P68371 2/20 0.58
TUBB3 Q13509 2/20 0.58
TUBB2A Q13885 2/20 0.58
TUBB8 Q3ZCM7 2/20 0.58
TUBA3E Q6PEY2 2/20 0.58
TUBA1A Q71U36 2/20 0.58
TUBA1C Q9BQE3 2/20 0.58
TUBB6 Q9BUF5 2/20 0.58
TUBB2B Q9BVA1 2/20 0.58
TUBB1 Q9H4B7 2/20 0.58
C5AR1 P21730 2/20 0.58
GHSR Q92847 5/20 0.55
KISS1R Q969F8 2/20 0.54
NPBWR1 P48145 2/20 0.53
IL23R Q5VWK5 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31680253 0.97 C5AR1 (0.61) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29641170 0.97 TUBB4A (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30132314 0.97 TUBB4A (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29641153 0.96 C5AR1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29461998 0.96 C5AR1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29540499 0.96 C5AR1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29884974 0.96 C5AR1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29540710 0.95 C5AR1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31680266 0.94 GHSR (0.60) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29461979 0.94 C5AR1 (0.56) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 EP disclosed
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 US disclosed
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 US disclosed
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING STEALTH BIOTHERAPEUTICS INC. (US) 2025-10-16 US disclosed
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 US disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 US disclosed
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-21 US disclosed
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-14 US disclosed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 EP disclosed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 US disclosed
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-22 US disclosed
US-11447523-B2 Methods for reducing CD36 expression CORNELL RESEARCH FOUNDATION, INC. (US) 2022-09-20 US disclosed
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-08 US disclosed
US-11420998-B2 Aromatic-cationic peptides and methods for using same STEALTH BIOTHERAPEUTICS INC. (US) 2022-08-23 US disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 EP disclosed
US-11312993-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2022-04-26 US disclosed
US-11266709-B2 Methods for the regulation of matrix metalloproteinase expression STEALTH BIOTHERAPEUTICS INC. (US) 2022-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME ARG2, ARGLU1, BCAT1 TUBB4A 3783/4885TUBB 2740/4885TUBA3C 3272/4885
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH TNNI3, TNNT2, FABP3 TUBB4A 1499/4885TUBB 1100/4885TUBA3C 1826/4885
US-12337023-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 TUBB4A 487/4885TUBB 1461/4885TUBA3C 1748/4885
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY NGF, GAP43, PRPH TUBB4A 2504/4885TUBB 1857/4885TUBA3C 2415/4885
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 TUBB4A 1020/4885TUBB 723/4885TUBA3C 1519/4885
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING ARG2, TNNT2, MYLK2 TUBB4A 2866/4885TUBB 2047/4885TUBA3C 2860/4885
US-11420998-B2 Aromatic-cationic peptides and methods for using same ARG2, ARGLU1, ARG1 TUBB4A 3784/4885TUBB 3411/4885TUBA3C 4442/4885
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS ARG2, MTPN, TNNT2 TUBB4A 4185/4885TUBB 4071/4885TUBA3C 4382/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 TUBB4A 487/4885TUBB 1461/4885TUBA3C 1748/4885
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 TUBB4A 1020/4885TUBB 723/4885TUBA3C 1519/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB TUBB4A 2163/4885TUBB 2056/4885TUBA3C 2787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.