SCHEMBL29538691

SCHEMBL29538691

CN(C)C(n1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 1/20 0.41
▸ TUBB P07437 1/20 0.41
▸ TUBA3C P0DPH7 1/20 0.41
▸ TUBA1B P68363 1/20 0.41
▸ TUBA4A P68366 1/20 0.41
▸ TUBB4B P68371 1/20 0.41
▸ TUBB3 Q13509 1/20 0.41
▸ TUBB2A Q13885 1/20 0.41
▸ TUBB8 Q3ZCM7 1/20 0.41
▸ TUBA3E Q6PEY2 1/20 0.41
▸ TUBA1A Q71U36 1/20 0.41
▸ TUBA1C Q9BQE3 1/20 0.41
▸ TUBB6 Q9BUF5 1/20 0.41
▸ TUBB2B Q9BVA1 1/20 0.41
▸ TUBB1 Q9H4B7 1/20 0.41
▸ FAAH O00519 4/20 0.40
▸ MGLL Q99685 4/20 0.40
▸ DGAT1 O75907 1/20 0.32
▸ PDE4B Q07343 1/20 0.31
▸ PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12019911 0.95 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29874491 0.92 TUBB4A (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL21073734 0.80 DGAT1 (0.51) DGAT1KDM4EALDH1A1MAPTHTT
SCHEMBL29369659 0.79 TUBB4A (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20591983 0.79 TUBB4A (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23088800 0.76 FAAH (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1516284 0.76 FAAH (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL65292 0.76 FAAH (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29351838 0.76 FAAH (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Hydrochloric Acid SCHEMBL20241832 0.75 FAAH (0.33) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728304-B1 SOLID PHASE SYNTHESIS OF ACYLATED PEPTIDES BACHEM HOLDING AG (CH) 2025-02-12 — — EP claimed
EP-4320138-B1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES BACHEM AG (CH) 2026-04-01 — — EP disclosed
US-12570679-B2 STAT3 protein degraders REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-03-10 — — US disclosed
US-12522623-B2 Small molecule STAT protein degraders REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-01-13 — — US disclosed
EP-4605403-B1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2025-11-26 — — EP disclosed
US-20250282813-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES BACHEM HOLDING AG (CH) 2025-09-11 — — US disclosed
EP-4605403-A1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS Bachem Holding AG (CH) 2025-08-27 — — EP disclosed
US-12240797-B2 Method of preparing a DON prodrug from L-glutamic acid DRACEN PHARMACEUTICALS, INC. (US) 2025-03-04 — — US disclosed
EP-3728304-B1 SOLID PHASE SYNTHESIS OF ACYLATED PEPTIDES BACHEM HOLDING AG (CH) 2025-02-12 — — EP disclosed
WO-2024083746-A1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2024-04-25 — — WO disclosed
EP-4201951-A1 METHOD FOR PEPTIDE SYNTHESIS Bachem Holding AG (CH) 2023-06-28 — — EP disclosed
US-20230159573-A1 SMALL MOLECULE STAT PROTEIN DEGRADERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-25 — — US disclosed
US-20230133504-A1 METHOD OF TREATING GRAFT-VERSUS-HOST DISEASE REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-05-04 — — US disclosed
US-20230083015-A1 SMALL MOLECULE DEGRADERS OF STAT3 UNIV MICHIGAN REGENTS (US) 2023-03-16 — — US disclosed
US-20230057232-A1 ISOTOPICALLY LABELED BILE ACID DERIVATIVES INTERCEPT PHARMACEUTICALS, INC. (US) 2023-02-23 — — US disclosed
US-11472831-B2 Isotopically labeled bile acid derivatives INTERCEPT PHARMACEUTICALS, INC. (US) 2022-10-18 — — US disclosed
WO-2022214692-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES BACHEM HOLDING AG (CH) 2022-10-13 — — WO disclosed
WO-2022187417-A1 SMALL MOLECULE DEGRADERS OF CBP/P300 PROTEINS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-09-09 — — WO disclosed
US-20220185831-A1 STAT3 PROTEIN DEGRADERS UNIV MICHIGAN REGENTS (US) 2022-06-16 — — US disclosed
US-20220089522-A1 METHOD OF PREPARING A DON PRODRUG FROM L-GLUTAMIC ACID DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C), AS COLLATERAL AGENT 2022-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089522-A1 METHOD OF PREPARING A DON PRODRUG FROM L-GLUTAMIC ACID GLUL, GLRA1, GRIN1 TUBB4A 4356/4885TUBB 3881/4885TUBA3C 3579/4885
US-20230083015-A1 SMALL MOLECULE DEGRADERS OF STAT3 STAT1, STAT3, JAK2 TUBB4A 3087/4885TUBB 2949/4885TUBA3C 4169/4885
US-20220185831-A1 STAT3 PROTEIN DEGRADERS STAT3, JAK2, STAT5A TUBB4A 2170/4885TUBB 2432/4885TUBA3C 3261/4885
US-12570679-B2 STAT3 protein degraders STAT3, JAK2, IL6ST TUBB4A 2297/4885TUBB 2204/4885TUBA3C 1697/4885
US-12240797-B2 Method of preparing a DON prodrug from L-glutamic acid GLUL, GLRA1, GLS TUBB4A 4385/4885TUBB 3831/4885TUBA3C 3514/4885
US-20230057232-A1 ISOTOPICALLY LABELED BILE ACID DERIVATIVES SLC10A2, SLC10A1, NR1H4 TUBB4A 127/4885TUBB 83/4885TUBA3C 191/4885
US-11472831-B2 Isotopically labeled bile acid derivatives SLC10A2, SLC10A1, NR1H4 TUBB4A 153/4885TUBB 117/4885TUBA3C 187/4885
US-20230133504-A1 METHOD OF TREATING GRAFT-VERSUS-HOST DISEASE HLA-DRB1, CD74, HLA-C TUBB4A 1127/4885TUBB 947/4885TUBA3C 2012/4885
US-20250282813-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES POLR2H, POLR2E, SUB1 TUBB4A 3295/4885TUBB 2589/4885TUBA3C 2626/4885
US-20230159573-A1 SMALL MOLECULE STAT PROTEIN DEGRADERS STAT1, STAT3, STAT5A TUBB4A 3076/4885TUBB 2876/4885TUBA3C 4045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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