Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 9/20 | 0.60 |
| ▸ | TUBB | P07437 | 9/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456102 | 0.79 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8938377 | 0.79 | MEN1 (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5806250 | 0.75 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28452235 | 0.70 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13698343 | 0.69 | HTR6 (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28461598 | 0.69 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8802574 | 0.68 | MTNR1A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10444002 | 0.68 | MTNR1A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12209489 | 0.68 | AKR1C2 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5313708 | 0.67 | HTR6 (0.67) | MAPTKMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479816-B2 | 20-HETE formation inhibitors | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-11-25 | — | — | US | disclosed |
| US-20220144797-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144797-A1 | 20-HETE FORMATION INHIBITORS | CYP4A22, ALOX5, ALOX15 | TUBB4A 941/4885TUBB 2488/4885TUBA3C 3428/4885 |
| US-12479816-B2 | 20-HETE formation inhibitors | CYP4A22, ALOX5, ALOX15 | TUBB4A 941/4885TUBB 2488/4885TUBA3C 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.