Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.36 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.35 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143011 | 0.75 | CA12 (0.39) | CA1CA12CA2CA7CA9 | |
| SCHEMBL30935736 | 0.72 | CA1 (0.58) | CA1CA2KDM4ELMNAL3MBTL1 | |
| SCHEMBL9339018 | 0.71 | CA12 (0.48) | CA1CA12CA2CA7CA9 | |
| SCHEMBL5586451 | 0.69 | LMNA (0.52) | CA1CA12CA2CA9LMNA | |
| SCHEMBL29249932 | 0.68 | POLB (0.53) | CA1CA12CA2CA7CA9 | |
| SCHEMBL28256201 | 0.68 | POLB (0.53) | CA1CA12CA2CA7CA9 | |
| SCHEMBL9815549 | 0.67 | PEPD (0.52) | CA1CA4CA5ACA5B | |
| Potassium Ion SCHEMBL29912532 | 0.67 | CA12 (0.48) | CA1CA12CA2CA7CA9 | |
| SCHEMBL4408905 | 0.67 | — | — | |
| SCHEMBL28993638 | 0.65 | TAS1R3 (0.37) | KDM4ELMNAL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344123-B2 | Cooling system of power storage device | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2025-07-01 | — | — | US | disclosed |
| CN-118428568-A | System and method for planning large-scale city custom-made traffic passenger line | 南京交通职业技术学院 | 2024-08-02 | — | — | CN | disclosed |
| CN-111987901-B | Driving device | 株式会社电装 | 2024-05-31 | — | — | CN | disclosed |
| US-20220388427-A1 | COOLING SYSTEM OF POWER STORAGE DEVICE | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2022-12-08 | — | — | US | disclosed |
| CN-115431752-A | Cooling system for power storage device | 丰田自动车株式会社 | 2022-12-06 | — | — | CN | disclosed |
| CN-114127277-A | Protease substrates and polypeptides comprising protease cleavage sequences | 中外制药株式会社 | 2022-03-01 | — | — | CN | disclosed |