SCHEMBL29641104

SCHEMBL29641104

N=C(N)NCCC[C@@H](N)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1CCCCC1)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 4/20 0.50
▸ NMT2 O60551 3/20 0.50
▸ CPB2 Q96IY4 8/20 0.49
▸ NPY4R P50391 3/20 0.48
▸ NPY1R P25929 2/20 0.48
▸ NPY2R P49146 2/20 0.48
▸ NPY5R Q15761 2/20 0.48
▸ CHRNB2 P17787 4/20 0.45
▸ CHRNB4 P30926 4/20 0.45
▸ CHRNA3 P32297 4/20 0.45
▸ CHRNA4 P43681 4/20 0.45
▸ GRIN1 Q05586 2/20 0.45
▸ GRIN2A Q12879 2/20 0.45
▸ GRM1 Q13255 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641028 0.97 CPB2 (0.50) NMT1NMT2CPB2NPY4RNPY1R
SCHEMBL22117559 0.94 NMT1 (0.50) NMT1NMT2CPB2NPY4RCHRNB2
SCHEMBL22117561 0.94 NMT1 (0.50) NMT1NMT2CPB2NPY4RCHRNB2
SCHEMBL22117473 0.93 NMT1 (0.48) NMT1NMT2CPB2NPY4RNPY1R
SCHEMBL22117472 0.93 NMT1 (0.48) NMT1NMT2CPB2NPY4RNPY1R
SCHEMBL29641218 0.92 CPB2 (0.59) NMT1NMT2CPB2
Hydrochloric Acid SCHEMBL31021010 0.92 NPY4R (0.48) NMT1NMT2CPB2NPY4RNPY1R
SCHEMBL30528168 0.89 NPY4R (0.45) NMT1NMT2CPB2NPY4RNPY1R
Hydrochloric Acid SCHEMBL31021035 0.88 NPY4R (0.44) NMT1NMT2CPB2NPY4RNPY1R
SCHEMBL31396825 0.86 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 — — US disclosed
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-22 — — US disclosed
US-20250051389-A1 AROMATIC-CATIONIC PEPTIDES AND USES OF SAME STEALTH BIOTHERAPEUTICS INC. (US) 2025-02-13 — — US disclosed
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2024-10-24 — — US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 — — US disclosed
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES STEALTH BIOTHERAPEUTICS INC. (US) 2024-02-22 — — US disclosed
EP-4233887-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2023-08-30 — — EP disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NMT1 2235/4885NMT2 1313/4885CPB2 137/4885
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES MTPN, CKMT1A; CKMT1B, TFAM NMT1 2324/4885NMT2 1490/4885CPB2 1110/4885
US-20250051389-A1 AROMATIC-CATIONIC PEPTIDES AND USES OF SAME ARG2, OAT, PDF NMT1 1728/4885NMT2 1056/4885CPB2 707/4885
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NMT1 2235/4885NMT2 1313/4885CPB2 137/4885
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF S100A10, SPG11, TMSB10 NMT1 1392/4885NMT2 1787/4885CPB2 558/4885
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY CRYAA, CRYAB, PRPH NMT1 2320/4885NMT2 1260/4885CPB2 1668/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB NMT1 3295/4885NMT2 2327/4885CPB2 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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