Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2965805 | 0.97 | KMT2A (0.59) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL2967742 | 0.89 | KMT2A (0.58) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL2973727 | 0.87 | KMT2A (0.59) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL28757542 | 0.87 | ALDH1A1 (0.57) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL7026435 | 0.87 | KMT2A (0.47) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL2967737 | 0.86 | KMT2A (0.58) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| Potassium Ion SCHEMBL2965809 | 0.86 | KMT2A (0.58) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL2965804 | 0.86 | KMT2A (0.58) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| Potassium Ion SCHEMBL2979884 | 0.84 | KMT2A (0.47) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| Potassium Ion SCHEMBL31252976 | 0.84 | ALDH1A1 (0.57) | KMT2AALDH1A1CYP3A4ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781611-B2 | Nitro-sulfobenzamides | AVENTIS CROPSCIENCE GMBH (DE) | 2010-08-24 | — | — | US | disclosed |
| EP-1242386-B1 | NITRO-SULFOBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1242386-A1 | NITRO-SULFOBENZAMIDES | Bayer CropScience GmbH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-20010020092-A1 | Nitro-sulfobenzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-09-06 | — | — | US | disclosed |
| WO-2001042226-A1 | NITRO-SULFOBENZAMIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020092-A1 | Nitro-sulfobenzamides | SULT1A1, SULT2A1, SULT1E1 | KMT2A 1005/4885ALDH1A1 605/4885CYP3A4 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.