SCHEMBL2974148

SCHEMBL2974148

O=C(CO)c1cc(O)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.59
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
CA7 P43166 4/20 0.59
CA9 Q16790 4/20 0.59
CA14 Q9ULX7 4/20 0.59
PTGS2 P35354 2/20 0.59
ALOX5 P09917 1/20 0.59
CHRNA7 P36544 4/20 0.53
HSP90AB1 P08238 1/20 0.52
ESR1 P03372 1/20 0.48
SHBG P04278 1/20 0.48
ESR2 Q92731 1/20 0.48
CES2 O00748 1/20 0.45
ACHE P22303 1/20 0.44
HTT P42858 1/20 0.44
NAAA Q02083 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105417 0.84 HSP90AB1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL7769565 0.84 CA12 (0.61) CA12CA1CA2CA7CA9
Water SCHEMBL1231468 0.83 HSP90AB1 (0.68) CA12CA1CA2CA7CA9
SCHEMBL1129352 0.81 HSP90AB1 (0.71) CA12CA1CA2CA7CA9
SCHEMBL3854857 0.81 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL29457562 0.81 HSP90AB1 (0.71) CA12CA1CA2CA7CA9
SCHEMBL21496861 0.80 CHRNA7 (0.55) CA12CA1CA2CA7CA9
SCHEMBL25666682 0.79 ALOX15 (0.64) CES2HTT
SCHEMBL9635504 0.79 CA1 (0.62) CA1CA2HTT
SCHEMBL12301087 0.79 CA12 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060269494-A1 New Ubiquitin-Proteasome Regulating Compounds and Their Application in Cosmetic and Pharmaceutical Formulations GUPTA SHYAM K 2006-11-30 US claimed
US-20060110415-A1 Topical Delivery System for Cosmetic and Pharmaceutical Agents BIODERM RESEARCH (US) 2006-05-25 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
WO-2023205439-A2 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. (US) 2023-10-26 WO disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-7834210-B2 Hair loss prevention by natural amino acid and peptide complexes BIODERM RESEARCH (US) 2010-11-16 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes BIODERM RESEARCH (US) 2009-10-08 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed
US-20060269494-A1 New Ubiquitin-Proteasome Regulating Compounds and Their Application in Cosmetic and Pharmaceutical Formulations GUPTA SHYAM K 2006-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 CA12 2732/4885CA1 2906/4885CA2 1234/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA CA12 4776/4885CA1 4867/4885CA2 4627/4885
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes MMP1, MMP17, MMP13 CA12 2559/4885CA1 3254/4885CA2 2859/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA CA12 4408/4885CA1 4577/4885CA2 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.