SCHEMBL2978683

SCHEMBL2978683

COc1c(C)cc(C(C)=O)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
TPMT P51580 5/20 0.49
TDP1 Q9NUW8 2/20 0.43
CA5A P35218 1/20 0.43
XDH P47989 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
NFKB1 P19838 1/20 0.42
GFER P55789 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
FUT7 Q11130 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 2/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2796551 0.88 LMNA (0.52) LMNATPMTCA5APOLBGFER
SCHEMBL21711825 0.85 TPMT (0.68) LMNATPMTTDP1CA5AXDH
SCHEMBL27898473 0.85 LMNA (0.62) LMNATPMTTDP1XDHKDM4E
SCHEMBL12245712 0.81 TPMT (0.73) LMNATPMTHTTTUBB4ATUBB
SCHEMBL786462 0.81 LMNA (0.60) LMNATPMTKDM4EPOLBGFER
SCHEMBL13293480 0.79 TUBB1 (0.44) LMNACA5APOLBGFERL3MBTL1
SCHEMBL9004046 0.78 HSD17B10 (0.46) LMNATPMTTDP1KDM4EALDH1A1
SCHEMBL1187957 0.77 LMNA (0.46) LMNATPMTTDP1CA5AXDH
SCHEMBL7554717 0.76 HTT (0.56) TPMTTDP1KDM4EGAAPOLB
SCHEMBL13144722 0.75 CA5A (0.50) LMNATDP1CA5AXDHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
EP-4510992-A2 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF Bobo Labs Inc. (US) 2025-02-26 EP disclosed
CN-119343126-A Skin barrier protection delivery system and method thereof 宝宝实验室公司 2025-01-21 CN disclosed
US-20250017830-A1 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. (US) 2025-01-16 US disclosed
US-12121603-B1 Skin barrier protective delivery systems BOBO LABS INC. (US) 2024-10-22 US disclosed
US-20240325265-A1 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. 2024-10-03 US disclosed
WO-2023205439-A2 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. (US) 2023-10-26 WO disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites BIODERM RESEARCH (US) 2009-05-21 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
US-20080287536-A1 Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes BIODERM RESEARCH (US) 2008-11-20 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US disclosed
EP-1944012-A1 SUNSCREEN COSMETIC COMPOSITION Shiseido Company, Limited (JP) 2008-07-16 EP disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 LMNA 1106/4885TPMT 3272/4885TDP1 2329/4885
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites TYR, MMP1, MMP17 LMNA 1587/4885TPMT 4391/4885TDP1 2801/4885
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 LMNA 167/4885TPMT 4577/4885TDP1 1464/4885
US-20080287536-A1 Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes MMP17, MC1R, TYR LMNA 691/4885TPMT 4623/4885TDP1 4206/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA LMNA 847/4885TPMT 4213/4885TDP1 3295/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA LMNA 641/4885TPMT 3516/4885TDP1 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.