Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 10/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PON1 | P27169 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893283 | 0.82 | ALDH1A1 (0.41) | HTR1DTSHR | |
| SCHEMBL1225503 | 0.81 | KDM4E (0.40) | RAPGEF4HRH3KDM4EPON1MAPK1 | |
| SCHEMBL21472699 | 0.80 | RAPGEF4 (0.40) | RAPGEF4TSHR | |
| SCHEMBL10849916 | 0.79 | HRH3 (0.36) | RAPGEF4HRH3KDM4EPON1MAPK1 | |
| SCHEMBL20669667 | 0.78 | PTGS2 (0.34) | RAPGEF4 | |
| SCHEMBL7983095 | 0.78 | HTR1D (0.40) | RAPGEF4HTR1DHTR1B | |
| SCHEMBL1255914 | 0.78 | HRH3 (0.32) | HRH3KDM4EPON1MAPK1RAB9A | |
| SCHEMBL2810221 | 0.77 | PGK1 (0.44) | HTR1D | |
| SCHEMBL2989162 | 0.76 | HTR1D (0.56) | HRH3PON1MAPK1RAB9AKMT2A | |
| SCHEMBL1316919 | 0.75 | HTR1D (0.48) | RAPGEF4HRH3KDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115805101-B | Catalyst for preparing hydroxy aryl ketone and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-116199612-B | Porous adsorbent and preparation method and application thereof | 荆楚理工学院 | 2024-06-21 | — | — | CN | claimed |
| CN-117003705-A | Novel 1,2, 3-triazole compound with anti-tumor effect, and preparation method and application thereof | 北京中医药大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-116135865-A | Preparation method of photoinitiator TPO | 安庆莱霆光电科技有限公司 | 2023-05-19 | — | — | CN | claimed |
| CN-115974055-A | Mesoporous multilayer spiral chiral nitrogen-doped carbon nanosphere and preparation method and application thereof | 山东复元新材料科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115805101-A | Catalyst for preparing hydroxy arone and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-114394895-A | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| EP-1344772-B1 | ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-07-22 | — | — | EP | claimed |
| US-7339082-B2 | Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-03-04 | — | — | US | claimed |
| US-20050070741-A1 | Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same | ISHIHARA KAZUAKI (JP) | 2005-03-31 | — | — | US | claimed |
| US-20040030192-A1 | Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-02-12 | — | — | US | claimed |
| EP-1344772-A1 | ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE | Japan Science and Technology Corporation (JP) | 2003-09-17 | — | — | EP | claimed |
| EP-0244819-B1 | Improved process for preparing substituted anthra[1,9-cd]-pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| EP-0244819-A2 | Improved process for preparing substituted anthra[1,9-cd]-pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1987-11-11 | — | — | EP | claimed |
| US-4672129-A | Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1987-06-09 | — | — | US | claimed |
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-26 | — | — | US | disclosed |
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2025-02-20 | — | — | US | disclosed |
| US-4053518-A | PROCESS FOR TRIS(ARALKYL)PHOSPHINES | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4017512-A | Process for producing N-alkylhydroxylamines | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | MC5R, CYP3A5, PTGIS | RAPGEF4 3983/4885HRH3 300/4885KDM4E 4082/4885 |
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | RAPGEF4 557/4885HRH3 2523/4885KDM4E 2973/4885 |
| US-20050070741-A1 | Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same | TTI1, TTI2, TST | RAPGEF4 2832/4885HRH3 3893/4885KDM4E 2308/4885 |
| US-20040030192-A1 | Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same | TTI1, TTI2, FLI1 | RAPGEF4 2949/4885HRH3 4027/4885KDM4E 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.