Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451162 | 0.84 | THRB (0.70) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL15214029 | 0.82 | THRB (0.45) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL16334846 | 0.82 | THRB (0.50) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL5224771 | 0.81 | THRB (0.48) | THRBPRKCICA9CA12CA1 | |
| SCHEMBL1520727 | 0.80 | CA12 (0.54) | THRBCYP3A4CA9CA12CA1 | |
| SCHEMBL14795733 | 0.79 | CYP3A4 (0.53) | THRBCYP3A4MEN1KMT2ACA9 | |
| SCHEMBL1878648 | 0.77 | THRB (0.61) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL29973339 | 0.76 | THRB (0.54) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL3280277 | 0.76 | THRB (0.54) | THRBPRKCICYP3A4MEN1HPGD | |
| SCHEMBL3957334 | 0.76 | TDP1 (0.47) | THRBCYP3A4HPGDCA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155311-A1 | SEPARATION OF CHIRAL ISOMERS BY SFC | DSM IP ASSETS B.V. (NL) | 2018-06-07 | — | — | US | disclosed |
| EP-3303314-A1 | SEPARATION OF CHIRAL ISOMERS BY SFC | DSM IP Assets B.V. (NL) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016188945-A1 | SEPARATION OF CHIRAL ISOMERS BY SFC | DSM IP ASSETS B.V. (NL) | 2016-12-01 | — | — | WO | disclosed |
| EP-2758366-B1 | PROCESS FOR PREPARING CHIRAL QUINONE | DSM IP ASSETS BV (NL) | 2016-04-27 | — | — | EP | disclosed |
| US-9045402-B2 | Process for preparing chiral quinone | DSM IP ASSETS B.V. (NL) | 2015-06-02 | — | — | US | disclosed |
| CN-103562159-B | Process of separating chiral isomers of chroman compounds and their derivatives and precursors | DSM IP ASSETS BV | 2015-04-15 | — | — | CN | disclosed |
| EP-2758366-A1 | PROCESS FOR PREPARING CHIRAL QUINONE | DSM IP Assets B.V. (NL) | 2014-07-30 | — | — | EP | disclosed |
| US-20140206905-A1 | PROCESS FOR PREPARING CHIRAL QUINONE | SAM IP ASSETS B.V. (NL) | 2014-07-24 | — | — | US | disclosed |
| CN-103562159-A | Process of separating chiral isomers of chroman compounds and their derivatives and precursors | DSM IP ASSETS BV | 2014-02-05 | — | — | CN | disclosed |
| WO-2013041676-A1 | PROCESS FOR PREPARING CHIRAL QUINONE | DSM IP ASSETS B.V. (NL) | 2013-03-28 | — | — | WO | disclosed |
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | BIODERM RESEARCH (US) | 2009-10-08 | — | — | US | disclosed |
| US-7572933-B2 | Skin and hair restoration by natural amino acid peptide complexes | BIODERM RESEARCH (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | disclosed |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | BIODERM RESEARCH (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | disclosed |
| US-7427690-B2 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration | BIODERM RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20070099886-A1 | Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration | BIODERM RESEARCH (US) | 2007-05-03 | — | — | US | disclosed |
| US-20050271608-A1 | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives | GUPTA SHYAM K | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206905-A1 | PROCESS FOR PREPARING CHIRAL QUINONE | SQLE, TTPA, VAT1 | THRB 3052/4885PRKCI 2712/4885CYP3A4 225/4885 |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | THRB 1199/4885PRKCI 2059/4885CYP3A4 1115/4885 |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | MMP17, MC1R, TYR | THRB 1495/4885PRKCI 1537/4885CYP3A4 3806/4885 |
| US-20180155311-A1 | SEPARATION OF CHIRAL ISOMERS BY SFC | VKORC1, VKORC1L1, TTPA | THRB 1521/4885PRKCI 2716/4885CYP3A4 209/4885 |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | PSMB1, PLOD3, CUTA | THRB 3874/4885PRKCI 887/4885CYP3A4 3624/4885 |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | MMP1, MMP17, MMP13 | THRB 2047/4885PRKCI 2396/4885CYP3A4 4008/4885 |
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | PROC, COL1A1, CUTA | THRB 2502/4885PRKCI 667/4885CYP3A4 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.