Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008366 | 0.90 | AR (0.32) | PGR | |
| SCHEMBL3228462 | 0.80 | BACE1 (0.38) | ALOX5ALDH1A1ESR2MEN1MAPT | |
| SCHEMBL29624141 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KIF11 | |
| SCHEMBL34188 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KIF11 | |
| SCHEMBL27780027 | 0.75 | KIF11 (0.48) | ALDH1A1ESR2MAPTESR1HSD17B10 | |
| SCHEMBL27991629 | 0.75 | RXRA (0.42) | ALOX5ALDH1A1RXRARXRBESR2 | |
| SCHEMBL3007873 | 0.74 | ESR1 (0.46) | ALDH1A1ESR2MEN1KMT2AESR1 | |
| SCHEMBL5928467 | 0.73 | NQO2 (0.37) | ALDH1A1HPGDALOX12HSD17B10 | |
| SCHEMBL4449613 | 0.73 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL25474285 | 0.72 | MAOA (0.40) | ALOX5ALDH1A1RXRARXRBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113255-A1 | NOVEL CARBONYLATION LIGANDS AND THEIR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-05-06 | — | — | US | claimed |
| EP-2794548-B1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INT UK LTD (GB) | 2019-05-15 | — | — | EP | disclosed |
| US-9809611-B2 | Carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-8445711-B2 | Metal complexes | LUCITE INTERNATIONAL UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20120309613-A1 | CARBONYLATION PROCESS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2012-12-06 | — | — | US | disclosed |
| US-20100197958-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-08-05 | — | — | US | disclosed |
| US-20100113255-A1 | NOVEL CARBONYLATION LIGANDS AND THEIR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
| US-20090312561-A1 | METAL COMPLEXES | LUCITE INTERNATIONAL UK LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197958-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | ALOX5, ACSL5, ELOVL5 | ALOX5 1/4885ALDH1A1 1228/4885RXRA 983/4885 |
| US-20090312561-A1 | METAL COMPLEXES | MLX, PICALM, AP2M1 | ALOX5 3585/4885ALDH1A1 3926/4885RXRA 3904/4885 |
| US-20100113255-A1 | NOVEL CARBONYLATION LIGANDS AND THEIR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | PRDX1, PRDX4, PRDX2 | ALOX5 987/4885ALDH1A1 865/4885RXRA 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.