Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502186 | 0.81 | HCAR3 (0.58) | ALDH1A1HCAR3HPGDTDP1ALDH3A1 | |
| SCHEMBL1888218 | 0.80 | HCAR3 (0.54) | ALDH1A1HCAR3ALDH3A1MAPTCRHBP | |
| SCHEMBL6156984 | 0.80 | CRHBP (0.65) | ALDH1A1HCAR3HPGDTDP1MAPT | |
| SCHEMBL129286 | 0.80 | HCAR3 (0.52) | ALDH1A1HCAR3TDP1MAPTL3MBTL1 | |
| SCHEMBL4626839 | 0.80 | TSHR (0.53) | ALDH1A1HCAR3GAACRHBPCRHR2 | |
| SCHEMBL211067 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HCAR3TDP1MAPTGAA | |
| SCHEMBL17846944 | 0.79 | L3MBTL1 (0.54) | ALDH1A1HCAR3TDP1MAPTL3MBTL1 | |
| SCHEMBL7591545 | 0.78 | MAPT (0.61) | ALDH1A1HPGDTDP1ALDH3A1MAPT | |
| SCHEMBL17939430 | 0.78 | KMT2A (0.52) | ALDH1A1HCAR3DOT1LTDP1ALDH3A1 | |
| SCHEMBL9680216 | 0.77 | ALDH1A1 (0.51) | ALDH1A1DOT1LHPGDTDP1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20050183212-A1 | Compositions for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one direct dye comprising an acid functional group, or a salt thereof, and processes using these compositions | L'OREAL S.A. (FR) | 2005-08-25 | — | — | US | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| WO-2024141614-A1 | COMPOSITION COMPRISING AT LEAST N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE DIRECT DYE, AT LEAST ONE CATIONIC POLYSACCHARIDE, AND AT LEAST ONE NON-CATIONIC POLYSACCHARIDE | L'OREAL (FR) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024133696-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A (POLY)CARBODIIMIDE COMPOUND, A COMPOUND CONTAINING AT LEAST ONE CARBOXYLIC ACID GROUP, AN AMINO SILICONE AND A COLOURING AGENT. | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| US-12016946-B2 | Process for the treatment of keratin fibers employing a composition comprising at least one alkoxysilane of formula (I), at least one non amino silicone of formula (II) having a weight-average molecular weight of less than or equal to 1500 g/mol and at least one coloring agent | L'OREAL (FR) | 2024-06-25 | — | — | US | disclosed |
| US-20240197615-A1 | HAIR COLOURING COMPOSITION COMPRISING AT LEAST ONE (POLY)CARBODIIMIDE COMPOUND AND AT LEAST ONE COMPOUND COMPRISING AT LEAST ONE HYDROXYL FUNCTION | L'OREAL (FR) | 2024-06-20 | — | — | US | disclosed |
| US-5874618-A | REACTING 2-NITRO-PARAPHENYLENEDIAMINES SUBSTITUTED AT 5-POSITION BY HALOGEN ATOM WITH MERCAPTAN DERIVATIVE OR SALT IN A SOLVENT, FURTHER OXIDIZING FOR SULFUR; USEFUL AS HAIR DYE; REDUCED ALLERGIES; WASHING STABILITY | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | disclosed |
| US-5735910-A | DIRECT HAIR DYES; WASHFASTNESS, COLORFASTNESS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | ALDH1A1 930/4885HCAR3 3774/4885DOT1L 102/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | ALDH1A1 385/4885HCAR3 3559/4885DOT1L 81/4885 |
| US-20050183212-A1 | Compositions for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one direct dye comprising an acid functional group, or a salt thereof, and processes using these compositions | KRT18, ADH5, ADH1C | ALDH1A1 20/4885HCAR3 3138/4885DOT1L 419/4885 |
| US-12016946-B2 | Process for the treatment of keratin fibers employing a composition comprising at least one alkoxysilane of formula (I), at least one non amino silicone of formula (II) having a weight-average molecular weight of less than or equal to 1500 g/mol and at least one coloring agent | KRT18, IK, MKI67 | ALDH1A1 1888/4885HCAR3 3934/4885DOT1L 588/4885 |
| US-20240197615-A1 | HAIR COLOURING COMPOSITION COMPRISING AT LEAST ONE (POLY)CARBODIIMIDE COMPOUND AND AT LEAST ONE COMPOUND COMPRISING AT LEAST ONE HYDROXYL FUNCTION | KRT18, PTMA, PRKDC | ALDH1A1 480/4885HCAR3 735/4885DOT1L 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.