Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 known ✓ | Q9H244 | 5/20 | 0.46 |
| ▸ | P2RY2 known ✓ | P41231 | 4/20 | 0.46 |
| ▸ | P2RY4 known ✓ | P51582 | 3/20 | 0.46 |
| ▸ | P2RY6 known ✓ | Q15077 | 3/20 | 0.46 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | FABP4 | P15090 | 1/20 | 0.70 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.68 |
| ▸ | FABP1 | P07148 | 1/20 | 0.54 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786498 | 1.00 | CDK2 (0.70) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL6654762 | 0.97 | CDK2 (0.70) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL30088900 | 0.97 | CDK2 (0.70) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL29837420 | 0.90 | CDK2 (0.84) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL1357870 | 0.90 | CDK2 (0.62) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL11215465 | 0.83 | FABP4 (0.72) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL43158 | 0.83 | FABP4 (1.00) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL29381891 | 0.83 | FABP4 (1.00) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL10353163 | 0.81 | FABP4 (0.97) | CDK2TTRFABP4CCNA2MAPK14 | |
| SCHEMBL6654772 | 0.81 | FABP4 (0.97) | CDK2TTRFABP4CCNA2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117701528-A | Plastic biodegradation mirror enzyme and application thereof | 中国农业大学 | 2024-03-15 | — | — | CN | disclosed |