SCHEMBL310771

SCHEMBL310771

COC(=O)c1ccc(O)c(C=O)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 10/20 0.77
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA12 O43570 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
XDH P47989 2/20 0.65
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 2/20 0.57
LMNA P02545 2/20 0.57
MEN1 O00255 1/20 0.57
TP53 P04637 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
ALOX12 P18054 1/20 0.57
HTT P42858 1/20 0.57
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153141 1.00 ERN1 (0.77) ERN1CA1CA2CA12CA7
SCHEMBL12767865 0.87 ERN1 (1.00) ERN1CA1CA2CA12CA7
SCHEMBL1485297 0.86 XDH (0.65) ERN1CA1CA2CA12CA7
SCHEMBL17747083 0.85 ALDH1A1 (0.58) ERN1CA1CA2CA12CA7
SCHEMBL5917939 0.84 CA1 (0.62) ERN1CA1CA2CA12CA7
SCHEMBL6640776 0.83 ERN1 (1.00) ERN1CA1CA2CA12CA9
SCHEMBL9125494 0.83 CA1 (0.61) ERN1CA1CA2CA12CA7
SCHEMBL9125499 0.83 CA1 (0.61) ERN1CA1CA2CA12CA7
SCHEMBL2316486 0.83 CA1 (0.61) ERN1CA1CA2CA12CA7
SCHEMBL3507686 0.82 ALDH1A1 (0.61) ERN1CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN claimed
US-20260138990-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260132160-A1 IRON REPLACEMENT TREATMENTS THE GENERAL HOSPITAL CORP (US) 2026-05-14 US disclosed
EP-4727947-A1 DYNAMIC COVALENT CHEMISTRY OF SPIROPYRANS FOR SYNTHESIS OF PHOTOSWITCHABLE PHOTOINITIATORS AND USES THEREOF Xolo GmbH (DE) 2026-04-22 EP disclosed
US-20260102962-A1 Dynamic Covalent Chemistry of Spiropyrans for Synthesis of Photoswitchable Photoinitiators and Uses Thereof, and Process for Locally Polymerizing a Starting Material by Dual Color Photopolymerization XOLO GMBH (DE) 2026-04-16 US disclosed
EP-4702026-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2026-03-04 EP disclosed
US-12564580-B2 Mitochondria-targeted isoketal/isolevuglandin scavengers and uses thereof VANDERBILT UNIVERSITY (US) 2026-03-03 US disclosed
US-12421257-B2 Compositions and methods for inhibiting group II intron RNA YALE UNIVERSITY (US) 2025-09-23 US disclosed
EP-4604943-A2 IRON REPLACEMENT TREATMENTS The General Hospital Corporation (US) 2025-08-27 EP disclosed
WO-2025122979-A1 COMPOUNDS FOR SEROTONIN RECEPTOR ACTIVATION AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME ATAI THERAPEUTICS, INC. (US) 2025-06-12 WO disclosed
US-5965741-A ANTIINFLAMMATORY, ANTIPYRETIC AND ANTIDIARRHOEAL PROPERTIES ZENECA LIMITED (GB) 1999-10-12 US disclosed
US-5863930-A ATHEROSCLEROSIS TREATMENT FORMED BY REACTION OF PYRIDONES WITH BIPHENYLMETHYL HALOGEN BAYER AKTIENGESELLSCHAFT (DE) 1999-01-26 US disclosed
US-5849798-A Polyaromatic heterocyclic compounds and pharmaceutical/cosmetic compositions comprised thereof CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 1998-12-15 US disclosed
EP-0778821-A1 ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF ZENECA LIMITED (GB) 1997-06-18 EP disclosed
US-5596006-A ANTIHYPERTENSIVE, ANTIATHEROSCLEROTIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-01-21 US disclosed
WO-1996006822-A1 ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF ZENECA LIMITED (GB) 1996-03-07 WO disclosed
WO-1995004046-A1 COMPOUNDS AS PDE IV AND TNF INHIBITORS RHONE-POULENC RORER LIMITED (GB) 1995-02-09 WO disclosed
EP-0594019-A1 Trisubstituted biphenyl as angiotensin II antagonistes BAYER AG (DE) 1994-04-27 EP disclosed
US-4272535-A 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents SCHERING CORPORATION (US) 1981-06-09 US disclosed
EP-0008277-A1 Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions Technobiotic Ltd. (CH) 1980-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421257-B2 Compositions and methods for inhibiting group II intron RNA NSUN2, RBM22, RNGTT ERN1 118/4885CA1 4407/4885CA2 3530/4885
US-20260138990-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF CD38, BCL9, BCL6B ERN1 2565/4885CA1 789/4885CA2 187/4885
US-12564580-B2 Mitochondria-targeted isoketal/isolevuglandin scavengers and uses thereof MAVS, AIFM1, TFAM ERN1 4027/4885CA1 4850/4885CA2 2389/4885
US-20260102962-A1 Dynamic Covalent Chemistry of Spiropyrans for Synthesis of Photoswitchable Photoinitiators and Uses Thereof, and Process for Locally Polymerizing a Starting Material by Dual Color Photopolymerization HTR3D, SPR, SRD5A1 ERN1 3657/4885CA1 3897/4885CA2 1728/4885
US-20260132160-A1 IRON REPLACEMENT TREATMENTS TFRC, SLC40A1, FTH1 ERN1 2586/4885CA1 645/4885CA2 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.