SCHEMBL310987

SCHEMBL310987

O=S(=O)([O-])c1ccc2cccccc1-2.[Na+]

nearest known ligand 0.52

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 known ✓ P35354 8/20 0.52
CA12 known ✓ O43570 2/20 0.42
CA1 known ✓ P00915 2/20 0.42
CA2 known ✓ P00918 2/20 0.42
PTGS1 known ✓ P23219 3/20 0.40
PKLR P30613 3/20 0.44
CA9 Q16790 2/20 0.42
PTPN1 P18031 3/20 0.41
PGAM1 P18669 2/20 0.41
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
BCAT2 O15382 1/20 0.39
MET P08581 1/20 0.39
HGF P14210 1/20 0.39
AKR1B1 P15121 1/20 0.39
FTO Q9C0B1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31323345 1.00 PTGS2 (0.52) PTGS2PKLRCA12CA1CA2
SCHEMBL28227505 1.00 PTGS2 (0.52) PTGS2PKLRCA12CA1CA2
Water SCHEMBL15672825 0.98 PTGS2 (0.50) PTGS2PKLRCA12CA1CA2
Water SCHEMBL31291030 0.98 PTGS2 (0.50) PTGS2PKLRCA12CA1CA2
Potassium Ion SCHEMBL14740336 0.96 PTGS2 (0.52) PTGS2PKLRCA12CA1CA2
SCHEMBL1870051 0.94 PTGS2 (0.48) PTGS2PKLRCA12CA1CA2
SCHEMBL29194064 0.94 PTGS2 (0.48) PTGS2PKLRCA12CA1CA2
SCHEMBL31276980 0.94 PTGS2 (0.48) PTGS2PKLRCA12CA1CA2
SCHEMBL28177146 0.91 PTGS2 (0.44) PTGS2PKLRCA12CA1CA2
Lithium Ion SCHEMBL3173871 0.89 PTGS2 (0.48) PTGS2PKLRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061694-A1 BIOCOMPATIBLE AND INJECTABLE PHOTOVOLTAIC RETINAL PROSTHESIS AARHUS UNIVERSITET (DK) 2025-03-27 WO claimed
CN-119139165-B Gum protecting toothpaste, preparation method thereof and gum protecting method 杭州纳美智康科技有限公司 2025-03-07 CN claimed
CN-119528772-A Preparation method of azulene sulfonamide 山东华素制药有限公司 2025-02-28 CN claimed
CN-222490069-U Reactor in continuous reaction process of sodium azulene sulfonate 山东华素制药有限公司 2025-02-18 CN claimed
CN-119454508-A Antiallergic cosmetic composition containing sodium azulene sulfonate as active ingredient 山东华素制药有限公司 2025-02-18 CN claimed
CN-119326675-A Compact whitening anti-allergy nursing essence and preparation method thereof 上海若梵生物科技有限公司 2025-01-21 CN claimed
CN-119235731-A Oral care solution with efficacy of improving oral health and preparation method thereof 苏州绿叶日用品有限公司 2025-01-03 CN claimed
CN-119192038-A Preparation method and application of sodium azulene sulfonate impurity 成都阿奇生物医药科技有限公司 2024-12-27 CN claimed
CN-119139165-A Gum protecting toothpaste, preparation method thereof and gum protecting method 杭州纳美智康科技有限公司 2024-12-17 CN claimed
CN-119015243-A Preparation method of sodium azulene sulfonate tablet with stable storage and long-acting release 山东华素制药有限公司 2024-11-26 CN claimed
CN-1803768-A Process for synthesizing stable sodium azulene sulfonate TIANJIN JING SHUO SCIENCE AND (CN) 2006-07-19 CN claimed
CN-1799539-A Compound glutamine granules and preparation method thereof HEILONGJIANG AOLIDA NAIDE PHAR (CN) 2006-07-12 CN claimed
EP-1666019-A1 COMPOSITION FOR APPLICATION TO TOOTH HANIX CO., LTD. (JP) 2006-06-07 EP claimed
CN-1561986-A Capsule agent containing L-glutamine and azulene sodium solfonate ZHANG HONGJUN (CN) 2005-01-12 CN claimed
CN-1430956-A Medicine for treating intestinal tract disease GUOKANG MEDICINE INDUSTRY CO L (CN) 2003-07-23 CN claimed
CN-1418620-A Quick disintegrated tablet or oral cavity disintegrated tablet containing L-glutamic acid and azulene sodium sulfonate and making method thereof KYOWA HAKKO KOGYO KK (JP) 2003-05-21 CN claimed
US-6146661-A WHICH CONTAINS ERYTHRITOL AND OPTIONALLY ANOTHER SUGAR ALCOHOL, WITH A DISSOLUTION ENDOTHERM OF 20 CAL OR MORE PER GRAM OF GASTROINTESTINAL DRUG, AND GASTROINTESTINAL DRUG SUCH AS SUCRALFATE; ORAL ADMINISTRATION WITHOUT WATER OR BAD TASTE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-11-14 US claimed
EP-0858801-A1 CHEWABLE TABLET Chugai Seiyaku Kabushiki Kaisha (JP) 1998-08-19 EP claimed
EP-0845265-A1 MUCOSAL PREPARATION CONTAINING PHYSIOLOGICALLY ACTIVE PEPTIDE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-06-03 EP claimed
CN-1179723-A Mucosal preparation containing physiologically active peptide ASAHI CHEMICAL IND (JP) 1998-04-22 CN claimed